RRC ID 85177
Author Saito R, Shimizu T, Kondoh A, Matsuyama T, Hisada A, Yaguchi T, Sato T, Mabuchi T.
Title [A Case of Phaeohyphomycosis Caused by Exophiala xenobiotica in an Immunocompromised Host].
Journal Med Mycol J
Abstract Phaeohyphomycosis is a rare subcutaneous fungal infection caused by melanin-containing brown-pigmented fungi. It typically occurs after skin injury in immunocompromised individuals. Herein, we report a case of phaeohyphomycosis caused by Exophiala xenobiotica in an immunocompromised elderly Japanese female. A subcutaneous mass on her left lower leg was totally removed but reappeared two months later. The subcutaneous mass resolved with additional seven months of 200 mg/day of oral itraconazole treatment. E. xenobiotica was identified as a new black yeast species in 2006. Genetic identification of the species was useful for identify the etiologic agent and choice of antifungal drugs.
Volume 66(1)
Pages 7-10
Published 2025-1-1
DOI 10.3314/mmj.24-00013
PMID 40024792
MeSH Aged Antifungal Agents / administration & dosage Antifungal Agents / therapeutic use Exophiala* / classification Exophiala* / genetics Exophiala* / isolation & purification Female Humans Immunocompromised Host* Itraconazole / administration & dosage Itraconazole / therapeutic use Phaeohyphomycosis* / diagnosis Phaeohyphomycosis* / drug therapy Phaeohyphomycosis* / microbiology Phaeohyphomycosis* / pathology Treatment Outcome
Resource
Pathogenic eukaryotic microorganisms Exophiala xenobiotica IFM 66862