論文 - 詳細
| RRC ID | 87542 |
|---|---|
| 著者 | Nishimura K, Asaoka M, Takano-Shimizu-Kouno T. |
| タイトル | Germline and male somatic determinants of sperm length divergence in Drosophila: Implications for post-copulatory sexual selection. |
| ジャーナル | Genetics |
| Abstract |
Sperm display remarkable diversity in size and morphology, especially in insects. Sperm length varies by several hundred-fold within Drosophila alone. In the model species Drosophila melanogaster, sperm are approximately 1.7 times longer than those of its close relatives D. simulans and D. mauritiana. However, the developmental mechanisms underlying such rapid divergence in sperm traits remain poorly understood. Somatic hub and cyst cells are essential for the maintenance of germline stem cells in Drosophila spermatogenesis, yet their contribution to cell growth later in spermatogenesis remains unclear. Here, we used primordial germ cell (PGC) xenotransplantation to determine whether sperm length regulation is cell-autonomous or influenced by the somatic environment of the testes. When D. simulans PGCs were transplanted into agametic D. melanogaster embryos, the resulting sperm were indistinguishable in length from those of D. simulans donor males and remained significantly shorter than the sperm of D. melanogaster males. Our results suggest that the dramatic diversification in sperm length shaped by post-copulatory sexual selection in the Drosophila lineage has been largely driven by cell-autonomous modifications in the germ line. |
| 公開日 | 2026-3-12 |
| DOI | 10.1093/genetics/iyag069 |
| PII | 8516363 |
| PMID | 41817134 |
| IF | 4.015 |
| オルトメトリクス指標 |
オルトメトリクス指標項目
|
| 最多言及媒体 | Bluesky |
| 各媒体での言及数の合計 | 6 |
| 過去6か月間でのオルトメトリクス指標の変動値 | 2.3 |
| リソース情報 | |
| ショウジョウバエ | DGRC#108217 DGRC#109173 DGRC#900020 DGRC#900018 |