RRC ID 87561
Author Cook KR.
Title The underappreciated, underrecognized problem of fourth chromosome trisomy in Drosophila melanogaster stocks and a simple, general method for building diplo-4 stocks from triplo-4 stocks.
Journal MicroPubl Biol
Abstract Trisomy of the small, fourth chromosome is common in Drosophila melanogaster stocks. Even though the presence of an extra chromosome can confound the interpretation of experimental crosses, many Drosophila geneticists are unaware of this potential problem. Here I describe a simple method employing a mutation in a haploinsufficient gene to recognize fourth chromosome trisomy and establish disomic stocks from trisomic stocks.
Volume 2025
Published 2025-1-1
DOI 10.17912/micropub.biology.001606
PMID 40385372
PMC PMC12082342
Resource
Drosophila DGRC#150529 DGRC#150531 DGRC#150532