論文 - 詳細
| RRC ID | 87941 |
|---|---|
| 著者 | Maeda K, Tamura Y, Nagai Y, Kariya Y, Katsuta H, Ajiro N, Yoshida H, Han Y, Hashimoto S, Chikamatsu K, Takaki A, Matsumoto Y, Fatimah RM, Tanaka M, Nakamura S, Iida T, Mitarai S, Nagai T. |
| タイトル | Non-tuberculous Mycobacterial pulmonary disease due to novel mycobacterium: Mycobacterium habikinoensis: a case report. |
| ジャーナル | BMC Infect Dis |
| Abstract |
BACKGROUND:The incidence of non-tuberculous mycobacterial pulmonary disease (NTM-PD) is increasing, and the identification of new Mycobacterium species is also increasing. We describe the first case of chronic pulmonary infection caused by a novel Mycobacterium species. CASE PRESENTATION:A 66-year-old man was referred to our hospital with a several-week history of low-grade fever and productive cough. An acid-fast bacillus smear test of the sputum revealed positive. Polymerase chain reaction (PCR) for Mycobacterium intracellulare was positive; however, Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) failed to identify the strain. The isolated culture was referred for further genotypic identification and was confirmed to be a novel species. Combination therapy with clarithromycin, rifampicin, and sitafloxacin was started. Despite treatment, the patient’s condition gradually worsened during the subsequent follow-up period. CONCLUSIONS:We describe the first case of NTM-PD with a novel Mycobacterium species. Mycobacterium habikinoensis is a novel species closely related to Mycobacterium colombiense but with distinct characteristics. Further investigation is required to clarify its pathogenicity, antimicrobial susceptibility, and clinical significance in human infections. SUPPLEMENTARY INFORMATION:The online version contains supplementary material available at 10.1186/s12879-026-12857-y. |
| 巻・号 | 26(1) |
| 公開日 | 2026-3-7 |
| DOI | 10.1186/s12879-026-12857-y |
| PII | 10.1186/s12879-026-12857-y |
| PMID | 41803767 |
| PMC | PMC13085733 |
| リソース情報 | |
| 病原細菌 | JNBP_31330 |