Reference - Detail
| RRC ID | 88703 |
|---|---|
| Author | Shiraishi T, Kutomi R, Sato Y, Endo A, Fukiya S, Takahashi S, Yokota A, Yokota SI. |
| Title | A unique tetrasaccharide-containing anchor glycolipid of lipoteichoic acid is commonly found in Lactobacillus gasseri and Lactobacillus paragasseri. |
| Journal | Biosci Biotechnol Biochem |
| Abstract |
Lipoteichoic acid (LTA) is a cell surface molecule with physiologically important roles in Gram-positive bacteria. Previously, we identified a novel tetrasaccharide-containing anchor glycolipid in the Lactobacillus gasseri JCM 1131T LTA. However, it is unclear whether this tetrasaccharide-containing anchor glycolipid structure is characteristic of JCM 1131T alone or is commonly found in other L. gasseri-related isolates. Lactobacillus paragasseri has been proposed as a new species, separated from the L. gasseri. In the present study, we characterized the chemical structures of LTA from 2 strains of L. gasseri and 4 strains of L. paragasseri. All 6 strains shared a polymer comprising repeating units of glycerophosphate with partial D-alanine substitutions, as well as L. gasseri JCM 1131T. Anchor glycolipid structure suggested that all strains shared a tetrasaccharide-containing glyceroglycolipid with 2 and 3 acyl groups. Focusing on LTA from L. gasseri and L. paragasseri species, a tetrasaccharide-containing anchor glycolipid is a specific feature. |
| Volume | 89(9) |
| Pages | 1382-1390 |
| Published | 2025-8-23 |
| DOI | 10.1093/bbb/zbaf081 |
| PII | 8155233 |
| PMID | 40455590 |
| MeSH | Glycolipids* / chemistry Lactobacillus* / chemistry Lactobacillus gasseri* / chemistry Lipopolysaccharides* / chemistry Oligosaccharides* / chemistry Teichoic Acids* / chemistry |
| Altmetric score |
オルトメトリクス指標項目
|
| The most frequently cited source | X(Twitter) |
| Total number of mentions | 2 |
| Altmetric score changes over past 6months | 0.0 |
| Resource | |
| General Microbes | JCM1131 JCM5814 JCM1130 |