| RRC ID |
88703
|
| Author |
Shiraishi T, Kutomi R, Sato Y, Endo A, Fukiya S, Takahashi S, Yokota A, Yokota SI.
|
| Title |
A unique tetrasaccharide-containing anchor glycolipid of lipoteichoic acid is commonly found in Lactobacillus gasseri and Lactobacillus paragasseri.
|
| Journal |
Biosci Biotechnol Biochem
|
| Abstract |
Lipoteichoic acid (LTA) is a cell surface molecule with physiologically important roles in Gram-positive bacteria. Previously, we identified a novel tetrasaccharide-containing anchor glycolipid in the Lactobacillus gasseri JCM 1131T LTA. However, it is unclear whether this tetrasaccharide-containing anchor glycolipid structure is characteristic of JCM 1131T alone or is commonly found in other L. gasseri-related isolates. Lactobacillus paragasseri has been proposed as a new species, separated from the L. gasseri. In the present study, we characterized the chemical structures of LTA from 2 strains of L. gasseri and 4 strains of L. paragasseri. All 6 strains shared a polymer comprising repeating units of glycerophosphate with partial D-alanine substitutions, as well as L. gasseri JCM 1131T. Anchor glycolipid structure suggested that all strains shared a tetrasaccharide-containing glyceroglycolipid with 2 and 3 acyl groups. Focusing on LTA from L. gasseri and L. paragasseri species, a tetrasaccharide-containing anchor glycolipid is a specific feature.
|
| Volume |
89(9)
|
| Pages |
1382-1390
|
| Published |
2025-8-23
|
| DOI |
10.1093/bbb/zbaf081
|
| PII |
8155233
|
| PMID |
40455590
|
| MeSH |
Glycolipids* / chemistry
Lactobacillus* / chemistry
Lactobacillus gasseri* / chemistry
Lipopolysaccharides* / chemistry
Oligosaccharides* / chemistry
Teichoic Acids* / chemistry
|
| Resource |
| General Microbes |
JCM1131
JCM5814
JCM1130 |
