Reference - Detail
| RRC ID | 88713 |
|---|---|
| Author | Li CJ, Zhang J, Su J, Yu LY, Chen HH, Zhang YQ. |
| Title | Genomic insights into Gordonia diversity: proposal of three novel species (Gordonia. altitudinis sp. nov., Gordonia. ligustrum sp. nov., and Gordonia. pistacia sp. nov.) with distinct environmental and biomedical traits. |
| Journal | BMC Microbiol |
| Abstract |
BACKGROUND:Rare actinomycetes, particularly Gordoni spp., are emerging as critical sources of bioactive metabolites and opportunistic pathogens. RESULTS:In this study, we isolated three novel Gordonia strains from soil samples and characterized their taxonomic status using a polyphasic taxonomic approach. Phylogenetic analysis of 16S rRNA genes and whole-genome comparisons indicated that strains CPCC 205333 T, CPCC 205515 T, and CPCC 206044 T represent three distinct novel species. The overall genome relatedness indices of average nucleotide identity (ANI) and digital DNA-DNA hybridization (dDDH) between these studied strains and their related type strains of the genus Gordonia were all below the established thresholds for species delineation, confirming the classification of these three as novel species, for which we propose the names Gordonia altitudinis sp. nov., Gordonia ligustrum sp. nov., and Gordonia pistacia sp. nov., respectively. Functional annotation revealed their ecological versatility, with Gordonia spp. contributing significantly to soil microbiome functionality through plant growth-promoting traits (e.g., nitrogen fixation, siderophore production) and biosynthetic gene clusters (BGCs), while also harboring virulence factors. Pan-genomic analysis of 225 Gordonia strains delineated an open gene pool (α = 0.82; 22% fluidity), reflecting adaptive plasticity. Core genomes were enriched in conserved metabolic pathways, whereas accessory and strain-specific genes showed niche-driven functional diversification, suggesting ecological specialization. CONCLUSION:These findings expand the genomic and functional understanding of Gordonia, highlighting its dual role in environmental resilience and pathogenicity, with potential applications in biotechnology and microbiome engineering. |
| Volume | 25(1) |
| Pages | 692 |
| Published | 2025-10-28 |
| DOI | 10.1186/s12866-025-04362-0 |
| PII | 10.1186/s12866-025-04362-0 |
| PMID | 41152715 |
| PMC | PMC12570513 |
| MeSH | Actinobacteria* / classification Actinobacteria* / genetics Bacterial Typing Techniques DNA, Bacterial / genetics Genome, Bacterial* Genomics Nucleic Acid Hybridization Phylogeny RNA, Ribosomal, 16S / genetics Sequence Analysis, DNA Soil Microbiology |
| Resource | |
| General Microbes | JCM10426 |