| RRC ID |
88866
|
| 著者 |
Ang Li Xuan A, Robert V, Hisatomi A, Hirasaki M, Maeno S, Ohkuma M, Sakamoto M, Chatel JM, Endo A.
|
| タイトル |
Faecalibacterium langellae sp. nov. isolated from human faeces.
|
| ジャーナル |
Int J Syst Evol Microbiol
|
| Abstract |
The genus Faecalibacterium is one of the major butyrate-producing bacteria in the human gut. Due to its production of beneficial metabolites and reduced populations in diseased patients, it is regarded as a potential biomarker of healthy gut microbiota. Strains Collection Nationale de Cultures de Microorganismes (CNCM) I-4540 and CNCM I-4541 were isolated from faeces of a healthy elderly and a healthy adult respectively. In this study, we conducted a taxonomic analysis of these strains. Phylogenetic analyses based on 16S rRNA gene and rpoA gene sequences revealed that the two strains belong to the genus Faecalibacterium. A core gene phylogenetic tree further supported their phylogenetic placement. CNCM I-4540 shared an average nucleotide identity (ANI) value of 96.7% and a digital DNA-DNA hybridization (dDDH) value of 74.3% with Faecalibacterium taiwanense HLW78T, indicating that CNCM I-4540 should be classified as F. taiwanense. In contrast, CNCM I-4541 did not exhibit ANI or dDDH values above the species threshold for any known species within the genus Faecalibacterium. These findings indicate that CNCM I-4541 represents a novel species within the genus Faecalibacterium, for which the name Faecalibacterium langellae sp. nov. is proposed. The type strain is CNCM I-4541T (=CIP 112513T=JCM 39552T).
|
| 巻・号 |
75(6)
|
| 公開日 |
2025-6-1
|
| DOI |
10.1099/ijsem.0.006804
|
| PMID |
40459242
|
| PMC |
PMC12281809
|
| MeSH |
Aged, 80 and over
Anaerobiosis
Faecalibacterium* / classification
Faecalibacterium* / isolation & purification
Faecalibacterium* / metabolism
Faecalibacterium* / ultrastructure
Feces* / microbiology
Humans
Male
Microscopy, Electron, Scanning
Middle Aged
Phylogeny
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| リソース情報 |
| 一般微生物 |
JCM39552 |
