論文 - 詳細
| RRC ID | 88866 |
|---|---|
| 著者 | Ang Li Xuan A, Robert V, Hisatomi A, Hirasaki M, Maeno S, Ohkuma M, Sakamoto M, Chatel JM, Endo A. |
| タイトル | Faecalibacterium langellae sp. nov. isolated from human faeces. |
| ジャーナル | Int J Syst Evol Microbiol |
| Abstract |
The genus Faecalibacterium is one of the major butyrate-producing bacteria in the human gut. Due to its production of beneficial metabolites and reduced populations in diseased patients, it is regarded as a potential biomarker of healthy gut microbiota. Strains Collection Nationale de Cultures de Microorganismes (CNCM) I-4540 and CNCM I-4541 were isolated from faeces of a healthy elderly and a healthy adult respectively. In this study, we conducted a taxonomic analysis of these strains. Phylogenetic analyses based on 16S rRNA gene and rpoA gene sequences revealed that the two strains belong to the genus Faecalibacterium. A core gene phylogenetic tree further supported their phylogenetic placement. CNCM I-4540 shared an average nucleotide identity (ANI) value of 96.7% and a digital DNA-DNA hybridization (dDDH) value of 74.3% with Faecalibacterium taiwanense HLW78T, indicating that CNCM I-4540 should be classified as F. taiwanense. In contrast, CNCM I-4541 did not exhibit ANI or dDDH values above the species threshold for any known species within the genus Faecalibacterium. These findings indicate that CNCM I-4541 represents a novel species within the genus Faecalibacterium, for which the name Faecalibacterium langellae sp. nov. is proposed. The type strain is CNCM I-4541T (=CIP 112513T=JCM 39552T). |
| 巻・号 | 75(6) |
| 公開日 | 2025-6-1 |
| DOI | 10.1099/ijsem.0.006804 |
| PMID | 40459242 |
| PMC | PMC12281809 |
| MeSH | Aged, 80 and over Anaerobiosis Faecalibacterium* / classification Faecalibacterium* / isolation & purification Faecalibacterium* / metabolism Faecalibacterium* / ultrastructure Feces* / microbiology Humans Male Microscopy, Electron, Scanning Middle Aged Phylogeny |
| オルトメトリクス指標 |
オルトメトリクス指標項目
|
| 最多言及媒体 | Bluesky |
| 各媒体での言及数の合計 | 1 |
| 過去6か月間でのオルトメトリクス指標の変動値 | 0.0 |
| リソース情報 | |
| 一般微生物 | JCM39552 |