論文 - 詳細
| RRC ID | 89843 |
|---|---|
| 著者 | Hara Y, Matsuoka Y, Takaya A, Ishibashi M. |
| タイトル | Two new mycobactins, mycobactins U and V, and their ferric complexes isolated from Mycolicibacterium septicum IFM 12283. |
| ジャーナル | J Nat Med |
| Abstract |
Two new mycobactins, U (1) and V (3), were isolated with ferric-1 (2) and ferric-3 (4) from the culture extracts of Mycolicibacterium septicum IFM 12283. The structures of compounds 1-4 were elucidated via spectral studies, including various NMR analyses. The absolute configurations of compounds 1-4 were deduced by comparing their circular dichroism (CD) spectra with those of mycobactin H (5) and ferric-mycobactin H (6). These compounds exhibited cytotoxicity against the MH7A rheumatoid fibroblast-like synovial cell line. |
| 巻・号 | 80(2) |
| ページ | 439-444 |
| 公開日 | 2026-3-1 |
| DOI | 10.1007/s11418-026-02007-8 |
| PII | 10.1007/s11418-026-02007-8 |
| PMID | 41634281 |
| MeSH | Cell Line Circular Dichroism Ferric Compounds* / chemistry Ferric Compounds* / isolation & purification Humans Magnetic Resonance Spectroscopy Molecular Structure Oxazoles |
| リソース情報 | |
| 病原真核微生物 | Mycolicibacterium septicum IFM 12283 |