| RRC ID |
928
|
| Author |
Koibuchi T, Takahashi T, Nakamura T, Suzuki M, Minamoto F, Oyaizu N, Yazawa K, Mikami Y, Iwamoto A.
|
| Title |
The first isolation of Nocardia nova from an HIV-1 infected individual in Japan.
|
| Journal |
J Infect Chemother
|
| Abstract |
Nocardia species are opportunistic pathogens of immunocompromised patients. We report a case of Nocardia nova infection complicating Pneumocystis carinii pneumonia (PCP) in an HIV-1 infected individual. A 27-year-old man with hemophilia A was admitted on October 17, 2000, with fever and dyspnea. CD4 cell counts were 5/microl on admission. Prophylaxis against PCP was administered by inhalation of pentamidine isethionate because he was allergic to sulfamethoxazole-trimethoprim (SMZ-TMP). He was diagnosed with PCP from chest X-ray and bronchoalveolar lavage. The sputum obtained for culture on admission was positive for Gram-positive branching rods; the organism was later identified as Nocardia nova. He died from respiratory failure on November 7, 2000. Although PCP might be a principal factor in respiratory failure, this case shows the need to consider pulmonary nocardiosis as a cause of respiratory illness in patients with advanced HIV-1 infection.
|
| Volume |
8(4)
|
| Pages |
358-60
|
| Published |
2002-12-1
|
| DOI |
10.1007/s10156-002-0189-3
|
| PII |
S1341-321X(02)71186-0
|
| PMID |
12525899
|
| MeSH |
Acquired Immunodeficiency Syndrome / microbiology*
Adult
HIV-1*
Humans
Male
Nocardia / isolation & purification*
Trimethoprim, Sulfamethoxazole Drug Combination / therapeutic use
|
| IF |
1.722
|
| Resource |
| Pathogenic microorganisms |
IFM 10022 |
