RRC ID 930
Author Myoken Y, Sugata T, Fujita Y, Asaoku H, Fujihara M, Mikami Y.
Title Fatal necrotizing stomatitis due to Trichoderma longibrachiatum in a neutropenic patient with malignant lymphoma: a case report.
Journal Int J Oral Maxillofac Surg
Abstract Primary invasive mold infection of the oral cavity is a rare but serious complication in immunocompromised hosts. We report a case of fatal Trichoderma longibrachiatum stomatitis in a 66-year-old female patient with malignant lymphoma. The infection rapidly disseminated from the oral mucosa to the lungs during neutropenia. Despite intensive antifungal therapy with amphotericin B and itraconazole, there was a fatal progression of the condition. While Trichoderma species have been recognized to be pathogenic in profoundly immunosuppressed hosts, this is the first report of the primary oral focus causing a fatal infection.
Volume 31(6)
Pages 688-91
Published 2002-12-1
DOI 10.1054/ijom.2001.0211
PII S0901-5027(01)90211-5
PMID 12521332
MeSH Aged Amphotericin B / therapeutic use Antifungal Agents / therapeutic use Disease Progression Fatal Outcome Female Gingivitis, Necrotizing Ulcerative / microbiology Humans Immunocompromised Host* Itraconazole / therapeutic use Lung Diseases, Fungal / microbiology Lymphoma, B-Cell / drug therapy* Lymphoma, Large B-Cell, Diffuse / drug therapy* Mycoses / microbiology* Neutropenia / etiology* Opportunistic Infections / microbiology Stomatitis / microbiology* Trichoderma*
IF 2.068
Times Cited 25
Pathogenic microorganisms T. longibrachiatum?