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Species Resource Title
Human and Animal Cells PC-9(RCB4455) Targeting the CAF-LPL-STAT3 axis mitigates osimertinib resistance associated with EGFR downregulation.
Human and Animal Cells HUDEP-2(RCB4557) BRD4 acts as a transcriptional repressor of RhoB to inhibit terminal erythropoiesis.
Human and Animal Cells HUDEP-2(RCB4557) SWI/SNF complex-mediated ZNF410 cooperative binding maintains chromatin accessibility and enhancer activity.
Human and Animal Cells HUDEP-2(RCB4557) A series of precise and controllable base editors with split-TadA-8e.
Human and Animal Cells HUDEP-2(RCB4557) Systematic identification and validation of ceRNA-driven regulatory mechanisms in pediatric β-Thalassemia major.
Human and Animal Cells HUDEP-2(RCB4557) A common TBP-binding site mutation elevates fetal hemoglobin levels by competitive globin switching change in β-thalassemia.
Human and Animal Cells HUDEP-2(RCB4557) MYB represses ζ-globin expression through upregulating ETO2.
Human and Animal Cells HUDEP-2(RCB4557) A one-base therapeutic insertion in the HBG2 distal promoter reactivates γ-globin expression.
Human and Animal Cells HUDEP-2(RCB4557) Therapeutic gene correction of HBB frameshift CD41-42 (-TCTT) deletion in human hematopoietic stem cells.
Human and Animal Cells HUDEP-2(RCB4557) Bioactive carbon dots from peony seed meal for nanomedicine via circular economy.
Human and Animal Cells HUDEP-2(RCB4557) In vivo genome editing of human haematopoietic stem cells for treatment of blood disorders using mRNA delivery.
Human and Animal Cells HUDEP-2(RCB4557) Circ_0001428 regulates erythropoiesis and γ-globin expression via activating the ATF4-BCL11A axis in β-thalassemia.
Human and Animal Cells HUDEP-2(RCB4557) The H3K4 methyltransferase KMT2D is an essential cofactor for GATA1 at erythroid gene enhancers.
Human and Animal Cells HUDEP-2(RCB4557) Triple base editor catalyzes saturation mutation of adenine, cytidine, and guanine.
Human and Animal Cells HUDEP-2(RCB4557) Discovery of a Novel DNMT1 Inhibitor with Improved Efficacy in Treating β-Thalassemia.
Human and Animal Cells HUDEP-2(RCB4557) A transcription factor-focused CRISPR screen identifies SKI as a BCL11A-independent repressor of ζ-globin.
Human and Animal Cells HUDEP-2(RCB4557) Identification of RBM3 as a novel regulator of human fetal hemoglobin expression.
Human and Animal Cells HUDEP-2(RCB4557) A scalable stem cell-derived erythroid cell system for the encapsulation and delivery of therapeutic enzymes: An in vitro proof-of-concept study.
Human and Animal Cells HCE-T(RCB2280) Honokiol Alleviates Dry Eye-Related Corneal Epithelial Damage by Activating SIRT3/PINK1-Mediated Mitophagy.
Human and Animal Cells MG6(RCB2403) Compartment-specific inhibition of cytosolic Cathepsin B mitigates microglial senescence in the aging brain.