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  • Search Condition : Filter (MeSH = AMP-Activated Protein Kinase Kinases)
Species Resource Title
Human and Animal Cells MCF7(RCB1904) Reactive nitrogen species regulate autophagy through ATM-AMPK-TSC2-mediated suppression of mTORC1.
Human and Animal Cells HuH-28(RCB1943) , RBE(RCB1292) , SSP-25(RCB1293) Underexpression of LKB1 tumor suppressor is associated with enhanced Wnt signaling and malignant characteristics of human intrahepatic cholangiocarcinoma.
Human and Animal Cells RBE(RCB1292) , HuH-28(RCB1943) Integrin β3 and LKB1 are independently involved in the inhibition of proliferation by lovastatin in human intrahepatic cholangiocarcinoma.
Human and Animal Cells SSP-25(RCB1293) , HuH-28(RCB1943) Lovastatin overcomes gefitinib resistance through TNF-α signaling in human cholangiocarcinomas with different LKB1 statuses in vitro and in vivo.
C.elegans tm1133 , tm1108 Neuronal TORC1 modulates longevity via AMPK and cell nonautonomous regulation of mitochondrial dynamics in C. elegans.
C.elegans tm2508 Suppression of AMPK/aak-2 by NRF2/SKN-1 down-regulates autophagy during prolonged oxidative stress.
Human and Animal Cells Hep G2(RCB1886) Metformin Regulates the Expression of CD133 Through the AMPK-CEBPβ Pathway in Hepatocellular Carcinoma Cell Lines.
C.elegans tm1944 Genome-wide surveys reveal polarity and cytoskeletal regulators mediate LKB1-associated germline stem cell quiescence.
Human and Animal Cells ST2(RCB0224) Phloretin Promotes Adipogenesis via Mitogen-Activated Protein Kinase Pathways in Mouse Marrow Stromal ST2 Cells.
Human and Animal Cells MKN1(RCB1003) , MKN45(RCB1001) , Kato III(RCB2088) The Antitumor Effects of Metformin on Gastric Cancer In Vitro and on Peritoneal Metastasis.
Human and Animal Cells MKN7(RCB0999) CAB39L elicited an anti-Warburg effect via a LKB1-AMPK-PGC1α axis to inhibit gastric tumorigenesis.
Drosophila 3051R-1 , 3051R-2 , 11871R-1 , 6715R-3 , 6715R-7 Drosophila LKB1 is required for the assembly of the polarized actin structure that allows spermatid individualization.
C.elegans tm1107 , tm1108 , tm1133 Dietary Restriction and AMPK Increase Lifespan via Mitochondrial Network and Peroxisome Remodeling.
C.elegans tm1944 Increased levels of hydrogen peroxide induce a HIF-1-dependent modification of lipid metabolism in AMPK compromised C. elegans dauer larvae.
Human and Animal Cells Prevalence and specificity of LKB1 genetic alterations in lung cancers.
Mice RBRC00806 Premature aging in mice activates a systemic metabolic response involving autophagy induction.