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  • Search Condition : Filter (MeSH = Alzheimer Disease* / metabolism)
Species Resource Title
DNA material pCAGGS-BLRP-BirA (RDB15774) Nuclear SphK2/S1P signaling is a key regulator of ApoE production and Aβ uptake in astrocytes.
Human and Animal Cells 201B7-Ff(HPS4290) Astrocyte-targeting therapy rescues cognitive impairment caused by neuroinflammation via the Nrf2 pathway.
Mice RBRC02370 Reduced progranulin increases tau and α-synuclein inclusions and alters mouse tauopathy phenotypes via glucocerebrosidase.
Mice RBRC03390 , RBRC03418 , RBRC06344 Apolipoprotein E genotype-dependent accumulation of amyloid β in APP-knock-in mouse model of Alzheimer's disease.
DNA material pCALNL5 (RDB01862) O-GalNAc glycosylation determines intracellular trafficking of APP and Aβ production.
Human and Animal Cells MG6(RCB2403) 3',4'-Dihydroxyflavonol Attenuates Lipopolysaccharide-Induced Neuroinflammatory Responses of Microglial Cells by Suppressing AKT-mTOR and NF-κB Pathways.
Human and Animal Cells 293(RCB1637) , THP-1(RCB1189) Alzheimer's Disease-Associated Alternative Splicing of CD33 Is Regulated by the HNRNPA Family Proteins.
Human and Animal Cells HPS0076 , HPS0360 , HPS3119 , HPS3131 , HPS3410 , HPS3417 , HPS3676 , HPS0254 , HPS0255 , HPS0256 , ... BMP4-SMAD1/5/9-RUNX2 pathway activation inhibits neurogenesis and oligodendrogenesis in Alzheimer's patients' iPSCs in senescence-related conditions.
Mice RBRC06344 , RBRC03390 , RBRC03418 Accumulation of amyloid-β in the brain of mouse models of Alzheimer's disease is modified by altered gene expression in the presence of human apoE isoforms during aging.
Mice RBRC06342 Distinct effects of SDC3 and FGFRL1 on selective neurodegeneration in AD and PD.
DNA material pCALNL5 (RDB01862) Endothelial expression of human amyloid precursor protein leads to amyloid β in the blood and induces cerebral amyloid angiopathy in knock-in mice.
Drosophila 18668R-2 Mical modulates Tau toxicity via cysteine oxidation in vivo.