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  • 検索条件 : 絞込み (MeSH = Autophagy-Related Protein-1 Homolog)
生物種 リソース名 タイトル
遺伝子材料 pMRX-IP-EGFP-mULK1 (RDB19624) Structures containing Atg9A and the ULK1 complex independently target depolarized mitochondria at initial stages of Parkin-mediated mitophagy.
遺伝子材料 pMXs-IP-EGFP-hATG13 (RDB19625) , pME18s-HA-hFIP200 (RDB19769) , pEGFP-C1-hAtg13 (RDB19770) , p3xFLAG-CMV10-hAtg13 (RDB19771) , p3xFLAG-CMV14-mULK1 (RDB19772) Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy.
遺伝子材料 pMXs-IP-EGFP-hFIP200 (RDB19623) , pMXs-IP-EGFP-mAtg5 (RDB19634) , p3xFLAG-CMV10-hFIP200 (RDB19762) , pMXs-IP-EGFP-ULK1(K46N) (RDB19780) , pMXs-IP-EGFP-LC3 (RDB19798) FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells.
ヒト・動物細胞 HuH-7 mTOR inhibitors synergize on regression, reversal of gene expression, and autophagy in hepatocellular carcinoma.
ショウジョウバエ atg7[d77] , atg7[d14] , atg8a[d4] , atg1[KG07993] Atg17/FIP200 localizes to perilysosomal Ref(2)P aggregates and promotes autophagy by activation of Atg1 in Drosophila.
実験動物マウス RBRC00806 Prior starvation mitigates acute doxorubicin cardiotoxicity through restoration of autophagy in affected cardiomyocytes.
ショウジョウバエ P[GawB]NP1626 (DGRC#112737) The class III PI(3)K Vps34 promotes autophagy and endocytosis but not TOR signaling in Drosophila.
ショウジョウバエ An Atg1/Atg13 complex with multiple roles in TOR-mediated autophagy regulation.