• 11 Hits
  • 検索条件 : 絞込み (MeSH = BRCA1 Protein / genetics)
生物種 リソース名 タイトル
ヒト・動物細胞 HEV0012(HEV0012) , 277-LCL(RCB2283) Evaluating homologous recombination activity in tissues to predict the risk of hereditary breast and ovarian cancer and olaparib sensitivity.
ヒト・動物細胞 Nips-B2(HPS0223) Keratinocytes from Gorlin Syndrome-induced pluripotent stem cells are resistant against UV radiation.
ヒト・動物細胞 JHOS-2(RCB1521) Endogenous DNA 3' Blocks Are Vulnerabilities for BRCA1 and BRCA2 Deficiency and Are Reversed by the APE2 Nuclease.
線虫 tm1145 , tm1813 The tumor suppressor BRCA1-BARD1 complex localizes to the synaptonemal complex and regulates recombination under meiotic dysfunction in Caenorhabditis elegans.
線虫 tm1145 , tm3298 , tm611 , tm574 BRCA1-BARD1 associate with the synaptonemal complex and pro-crossover factors and influence RAD-51 dynamics during Caenorhabditis elegans meiosis.
ヒト・動物細胞 HeLa/Fucci(RCB2812) BRCA2 controls DNA:RNA hybrid level at DSBs by mediating RNase H2 recruitment.
ヒト・動物細胞 MCF7(RCB1904) The HSF1-PARP13-PARP1 complex facilitates DNA repair and promotes mammary tumorigenesis.
ヒト・動物細胞 HBL-100(RCB0460) Abnormal expression of BRCA1 and BRCA1-interactive DNA-repair proteins in breast carcinomas.
遺伝子材料 chk1+ (RDB02949) , crb2+ (RDB02950). Damage and replication checkpoint control in fission yeast is ensured by interactions of Crb2, a protein with BRCT motif, with Cut5 and Chk1.
線虫 tm1145 , tm853 A conserved pathway to activate BRCA1-dependent ubiquitylation at DNA damage sites.
線虫 tm1145 BRCA1-mediated ubiquitylation.