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Species Resource Title
Mice RBRC06344 Selective suppression of oligodendrocyte-derived amyloid beta rescues neuronal dysfunction in Alzheimer's disease.
Mice RBRC00999 Expression of kinase-deficient MEK2 ameliorates Pelizaeus-Merzbacher disease phenotypes in mice.
Mice RBRC06240 Peripheral HMGB1 is linked to O3 pathology of disease-associated astrocytes and amyloid.
Mice RBRC06344 Probiotic Bifidobacterium breve Prevents Memory Impairment Through the Reduction of Both Amyloid-β Production and Microglia Activation in APP Knock-In Mouse.
Human and Animal Cells 293(RCB1637) Nogo-A and nogo receptor expression in demyelinating lesions of multiple sclerosis.
Zebrafish Tg(Huc:Kaede)rw0130a Establishing a high throughput drug screening system for cerebral ischemia using zebrafish larvae.
Drosophila 11144R-3 Downregulation of glial genes involved in synaptic function mitigates Huntington's disease pathogenesis.
Human and Animal Cells 201B7(HPS0063) Acid sphingomyelinase modulates the autophagic process by controlling lysosomal biogenesis in Alzheimer's disease.
Human and Animal Cells NB2a(RCB2639) Epigenetic regulation of the glucose transporter gene Slc2a1 by β-hydroxybutyrate underlies preferential glucose supply to the brain of fasted mice.
C.elegans tm1264 , tm1312 , tm1182 , tm869 , tm1339 Distinct Poly(A) nucleases have differential impact on sut-2 dependent tauopathy phenotypes.
Human and Animal Cells 293T(RCB2202) Cytosolic dsDNA of mitochondrial origin induces cytotoxicity and neurodegeneration in cellular and zebrafish models of Parkinson's disease.
Human and Animal Cells MG6(RCB2403) Progranulin regulates lysosomal function and biogenesis through acidification of lysosomes.
Drosophila DGRC#140400 Functional assessment of the "two-hit" model for neurodevelopmental defects in Drosophila and X. laevis.
Human and Animal Cells MG6(RCB2403) Photo-oxygenation by a biocompatible catalyst reduces amyloid-β levels in Alzheimer's disease mice.
Drosophila 2155R-2 , 3757R-5 , 8221R-4 , 8221R-1 Proteasome stress in skeletal muscle mounts a long-range protective response that delays retinal and brain aging.
Human and Animal Cells PC-12(RCB0009) Contribution of DHA diols (19,20-DHDP) produced by cytochrome P450s and soluble epoxide hydrolase to the beneficial effects of DHA supplementation in the brains of rotenone-induced rat models of Parkinson's disease.
Mice RBRC05796 A non-mosaic transchromosomic mouse model of down syndrome carrying the long arm of human chromosome 21.
Human and Animal Cells P19.CL6(RCB1539) RRP7A links primary microcephaly to dysfunction of ribosome biogenesis, resorption of primary cilia, and neurogenesis.
Human and Animal Cells Atg5^(+/+)MEF(RCB2710) , Atg5^(-/-)MEF(RCB2711) Fbxo2 mediates clearance of damaged lysosomes and modifies neurodegeneration in the Niemann-Pick C brain.
Human and Animal Cells NB2a(RCB2639) Trichloroethylene exposure aggravates behavioral abnormalities in mice that are deficient in superoxide dismutase.