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  • 46 Hits
  • 検索条件 : 絞込み (MeSH = Drug Design)
生物種 リソース名 タイトル
ヒト・動物細胞 HeLa S3 , A549 , PC-3 Synthetic prodrug design enables biocatalytic activation in mice to elicit tumor growth suppression.
ヒト・動物細胞 HCT116(RCB2979) In Vitro and In Silico Study of Analogs of Plant Product Plastoquinone to Be Effective in Colorectal Cancer Treatment.
ヒト・動物細胞 MC3T3-E1(RCB1126) Novel therapeutic agents for bone resorption. Part 1. Synthesis and protonation thermodynamics of poly(amido-amine)s containing bis-phosphonate residues.
ヒト・動物細胞 HGC-27(RCB0500) Discovery of novel ceramide analogs with favorable pharmacokinetic properties and combination with AKT inhibitor against colon cancer.
ヒト・動物細胞 HCE-T(RCB2280) Cellular uptake of coumarin-6 under microfluidic conditions into HCE-T cells from nanoscale formulations.
ヒト・動物細胞 CW-2(RCB0778) , MKN-7(RCB3687) Engineering an anti-HER2 biparatopic antibody with a multimodal mechanism of action.
ヒト・動物細胞 IMR-32(RCB1895) , LA-N-1(RCB0483) , SK-N-SH(RCB0426) Sesquiterpene lactones derived from Saussurea lappa induce apoptosis and inhibit invasion and migration in neuroblastoma cells.
ヒト・動物細胞 HeLa(RCB0007) Screening, Synthesis, and Evaluation of Novel Isoflavone Derivatives as Inhibitors of Human Golgi β-Galactosidase.
ヒト・動物細胞 NB1RGB(RCB0222) Synthesis and biological activity of thiazolyl-acetic acid derivatives as possible antimicrobial agents.
ヒト・動物細胞 HeLa Design Strategy to Create Antibody Mimetics Harbouring Immobilised Complementarity Determining Region Peptides for Practical Use.
ヒト・動物細胞 HeLa S3 (SC)(RCB0271) Relationship among structure, cytotoxicity, and Michael acceptor reactivity of quinocidin.
ヒト・動物細胞 MCF7(RCB1904) , HeLa , Hep G2 , HCT116(RCB2979) Design, Synthesis and Anticancer Evaluation of New Substituted Thiophene-Quinoline Derivatives.
ヒト・動物細胞 A431(RCB0202) Inhibition of EGFR Activation by Bivalent Ligands Based on a Cyclic Peptide Mimicking the Dimerization Arm Structure of EGFR.
ヒト・動物細胞 Colon-26(RCB2657) Lamellarin-inspired potent topoisomerase I inhibitors with the unprecedented benzo[g][1]benzopyrano[4,3-b]indol-6(13H)-one scaffold.
ヒト・動物細胞 COS-7(RCB0539) Structure and mechanism of cancer-associated N-acetylglucosaminyltransferase-V.
一般微生物 JCM 20379 In silico structure-based drug screening of novel antimycobacterial pharmacophores by DOCK-GOLD tandem screening.
ヒト・動物細胞 COS-7(RCB0539) Na+-mimicking ligands stabilize the inactive state of leukotriene B4 receptor BLT1.
ヒト・動物細胞 PC-12(RCB0009) Site-specific aspartic acid isomerization regulates self-assembly and neurotoxicity of amyloid-β.
ヒト・動物細胞 KP4(RCB1005) Monovalent antibody design and mechanism of action of onartuzumab, a MET antagonist with anti-tumor activity as a therapeutic agent.
ヒト・動物細胞 Development of an orally-administrative MELK-targeting inhibitor that suppresses the growth of various types of human cancer.