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  • Search Condition : Filter (MeSH = ErbB Receptors / antagonists & inhibitors*)
Species Resource Title
Drosophila EGFRAP encodes a new negative regulator of the EGFR acting in both normal and oncogenic EGFR/Ras-driven tissue morphogenesis.
Human and Animal Cells RERF-LC-KJ(RCB1313) , LC-1/sq(RCB0455) , RERF-LC-AI(RCB0444) , MS-1(RCB0725) PTEN inactivation in lung cancer cells and the effect of its recovery on treatment with epidermal growth factor receptor tyrosine kinase inhibitors.
Human and Animal Cells PC-9(RCB4455) Discovery of N-((3R,4R)-4-Fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)-9-methyl-9H-purin-2-yl)pyrrolidine-3-yl)acrylamide (PF-06747775) through Structure-Based Drug Design: A High Affinity Irreversible Inhibitor Targeting Oncogenic EGFR Mutants with Selectivity over Wild-Type EGFR.
Human and Animal Cells PC-9(RCB4455) Discovery of 1-{(3R,4R)-3-[({5-Chloro-2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)methyl]-4-methoxypyrrolidin-1-yl}prop-2-en-1-one (PF-06459988), a Potent, WT Sparing, Irreversible Inhibitor of T790M-Containing EGFR Mutants.
Human and Animal Cells PC-9(RCB4455) Resminostat, a histone deacetylase inhibitor, circumvents tolerance to EGFR inhibitors in EGFR-mutated lung cancer cells with BIM deletion polymorphism.
Human and Animal Cells RERF-LC-AI(RCB0444) , EBC-1(RCB1965) Docetaxel Upregulates HMGB1 Levels in Non-small Cell Lung Cancer.
Human and Animal Cells A431(RCB0202) Inhibition of EGFR Activation by Bivalent Ligands Based on a Cyclic Peptide Mimicking the Dimerization Arm Structure of EGFR.
Human and Animal Cells A431(RCB0202) Soluble Expression in Escherichia coli of a Single-Domain Antibody-Tumor Necrosis Factor α Fusion Protein Specific for Epidermal Growth Factor Receptor.
Human and Animal Cells PC-9(RCB4455) The Significance of MMP-1 in EGFR-TKI-Resistant Lung Adenocarcinoma: Potential for Therapeutic Targeting.
Human and Animal Cells TE-1(RCB1894) , TE-5(RCB1949) , TE-8(RCB2098) , TE-11(RCB2100) Distinct effects of EGFR inhibitors on epithelial- and mesenchymal-like esophageal squamous cell carcinoma cells.
Human and Animal Cells 293(RCB1637) Up-Regulation of Transient Receptor Potential Melastatin 6 Channel Expression by Tumor Necrosis Factor-α in the Presence of Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor.
Human and Animal Cells TE-5(RCB1949) , TE-8(RCB2098) , TE-10(RCB2099) , TE-1(RCB1894) Novel EGFR-targeted strategy with hybrid peptide against oesophageal squamous cell carcinoma.
C.elegans tm3256 Royalactin extends lifespan of Caenorhabditis elegans through epidermal growth factor signaling.
Human and Animal Cells Tumor-derived TGF-β and prostaglandin E2 attenuate anti-tumor immune responses in head and neck squamous cell carcinoma treated with EGFR inhibitor.
Human and Animal Cells CW-2(RCB0778) Heterogeneous EGFR gene copy number increase is common in colorectal cancer and defines response to anti-EGFR therapy.
Human and Animal Cells MRC-5 Ability of the Met kinase inhibitor crizotinib and new generation EGFR inhibitors to overcome resistance to EGFR inhibitors.
Human and Animal Cells Ho-1-u-1(RCB2102) , HSC-2(RCB1945) , HSC-3(RCB1975) , HSC-4(RCB1902) , Sa3(RCB0980) EGFR inhibitors augment antitumour helper T-cell responses of HER family-specific immunotherapy.
Human and Animal Cells EBC-1(RCB1965) Enhanced antitumor activity of erlotinib in combination with the Hsp90 inhibitor CH5164840 against non-small-cell lung cancer.
Human and Animal Cells MKN1(RCB1003) Monitoring the cytoskeletal EGF response in live gastric carcinoma cells.
Human and Animal Cells TGBC1TKB(RCB1129) Targeting EGFR/HER2 pathways enhances the antiproliferative effect of gemcitabine in biliary tract and gallbladder carcinomas.