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  • Search Condition : Filter (MeSH = F-Box-WD Repeat-Containing Protein 7)
Species Resource Title
Human and Animal Cells OP9(RCB1124) Ablation of Fbxw7 eliminates leukemia-initiating cells by preventing quiescence.
Human and Animal Cells K562(RCB0027) Fbw7 promotes ubiquitin-dependent degradation of c-Myb: involvement of GSK3-mediated phosphorylation of Thr-572 in mouse c-Myb.
Human and Animal Cells HuCCT1(RCB1960) FBXW7 suppresses epithelial-mesenchymal transition, stemness and metastatic potential of cholangiocarcinoma cells.
Human and Animal Cells HHUA(RCB0658) CCNE1 amplification is associated with aggressive potential in endometrioid endometrial carcinomas.
Human and Animal Cells K562 Regulation of GATA-binding protein 2 levels via ubiquitin-dependent degradation by Fbw7: involvement of cyclin B-cyclin-dependent kinase 1-mediated phosphorylation of THR176 in GATA-binding protein 2.
DNA material AxCANCre (RDB01748) , AxCANLacZ (RDB01749). Skp1-Cullin-F-box (SCF)-type ubiquitin ligase FBXW7 negatively regulates spermatogonial stem cell self-renewal.
DNA material AxCANCre (RDB01748) Inhibition of ubiquitin ligase F-box and WD repeat domain-containing 7α (Fbw7α) causes hepatosteatosis through Krüppel-like factor 5 (KLF5)/peroxisome proliferator-activated receptor γ2 (PPARγ2) pathway but not SREBP-1c protein in mice.