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10 Hits
検索条件 : 絞込み (MeSH = Fetal Hemoglobin / metabolism)
生物種
リソース名
RRC ID
タイトル
ジャーナル
公開日
外部リンク
ヒト・動物細胞
HUDEP-2(RCB4557)
77350
Editing a γ-globin repressor binding site restores fetal hemoglobin synthesis and corrects the sickle cell disease phenotype.
Sci Adv
2020-2-1
Pubmed
Full text
ヒト・動物細胞
HUDEP-2(RCB4557)
77345
Targeting fetal hemoglobin expression to treat β hemoglobinopathies.
Expert Opin Ther Targets
2022-4-1
Pubmed
Full text
ヒト・動物細胞
HUDEP-2(RCB4557)
77304
A unified model of human hemoglobin switching through single-cell genome editing.
Nat Commun
2021-8-17
Pubmed
Full text
ヒト・動物細胞
HUDEP-2(RCB4557)
77301
ZNF410 Uniquely Activates the NuRD Component CHD4 to Silence Fetal Hemoglobin Expression.
Mol Cell
2021-1-21
Pubmed
Full text
ヒト・動物細胞
HUDEP-1(RCB4556)
,
HUDEP-2(RCB4557)
77297
Pharmacologic induction of PGC-1α stimulates fetal haemoglobin gene expression.
Br J Haematol
2022-4-1
Pubmed
Full text
ヒト・動物細胞
HUDEP-2(RCB4557)
77232
Disrupting the adult globin promoter alleviates promoter competition and reactivates fetal globin gene expression.
Blood
2022-4-7
Pubmed
Full text
ヒト・動物細胞
HUDEP-2(RCB4557)
73469
Evolution of nanobodies specific for BCL11A.
Proc Natl Acad Sci U S A
2023-1-17
Pubmed
Full text
ヒト・動物細胞
HUDEP-2(RCB4557)
73033
Base-editing-mediated dissection of a γ-globin cis-regulatory element for the therapeutic reactivation of fetal hemoglobin expression.
Nat Commun
2022-11-4
Pubmed
Full text
ヒト・動物細胞
HUDEP-1(RCB4556)
,
HUDEP-2(RCB4557)
69376
Transcription factor competition at the γ-globin promoters controls hemoglobin switching.
Nat Genet
2021-4-1
Pubmed
Full text
ヒト・動物細胞
HUDEP-2(RCB4557)
,
HUDEP-1(RCB4556)
61923
Phenotypic-screening generates active novel fetal globin-inducers that downregulate Bcl11a in a monkey model.
Biochem Pharmacol
2020-1-1
Pubmed
Full text