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  • 11 Hits
  • Search Condition : Filter (MeSH = Fusion Proteins, bcr-abl / genetics)
Species Resource Title
Human and Animal Cells K562 TOPK is regulated by PP2A and BCR/ABL in leukemia and enhances cell proliferation.
Human and Animal Cells Inhibition of the PI3K/Akt/GSK3 pathway downstream of BCR/ABL, Jak2-V617F, or FLT3-ITD downregulates DNA damage-induced Chk1 activation as well as G2/M arrest and prominently enhances induction of apoptosis.
Human and Animal Cells Imatinib induces demethylation of miR-203 gene: an epigenetic mechanism of anti-tumor effect of imatinib.
Human and Animal Cells ATM-dependent DNA damage-response pathway as a determinant in chronic myelogenous leukemia.
Human and Animal Cells PECAM-1 is involved in BCR/ABL signaling and may downregulate imatinib-induced apoptosis of Philadelphia chromosome-positive leukemia cells.
Human and Animal Cells Effect of arsenic trioxide on different cell lines derived from chronic myeloid leukemia.
Human and Animal Cells Enhancement of imatinib-induced apoptosis of BCR/ABL-expressing cells by nutlin-3 through synergistic activation of the mitochondrial apoptotic pathway.
Human and Animal Cells The anti-apoptotic role of the unfolded protein response in Bcr-Abl-positive leukemia cells.
Human and Animal Cells Sorafenib induces apoptosis specifically in cells expressing BCR/ABL by inhibiting its kinase activity to activate the intrinsic mitochondrial pathway.
Mice B6.Cg-Tg(Tec-p210 BCR/ABL1)1Homy(RBRC02339) NADPH oxidases as therapeutic targets in chronic myelogenous leukemia.
Mice Floxed RBP-J Regulation of myeloid leukaemia by the cell-fate determinant Musashi.