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  • 9 Hits
  • Search Condition : Filter (MeSH = Fusion Proteins, bcr-abl / metabolism*)
Species Resource Title
Human and Animal Cells K562 TOPK is regulated by PP2A and BCR/ABL in leukemia and enhances cell proliferation.
Human and Animal Cells Ba/F3-CL1(RCB4474) Localization of BCR-ABL to Stress Granules Contributes to Its Oncogenic Function.
Human and Animal Cells Ba/F3(RCB0805) Taxodione induces apoptosis in BCR-ABL-positive cells through ROS generation.
Human and Animal Cells Inhibition of the PI3K/Akt/GSK3 pathway downstream of BCR/ABL, Jak2-V617F, or FLT3-ITD downregulates DNA damage-induced Chk1 activation as well as G2/M arrest and prominently enhances induction of apoptosis.
Human and Animal Cells PECAM-1 is involved in BCR/ABL signaling and may downregulate imatinib-induced apoptosis of Philadelphia chromosome-positive leukemia cells.
Human and Animal Cells Functional cooperation among Ras, STAT5, and phosphatidylinositol 3-kinase is required for full oncogenic activities of BCR/ABL in K562 cells.
Human and Animal Cells Enhancement of imatinib-induced apoptosis of BCR/ABL-expressing cells by nutlin-3 through synergistic activation of the mitochondrial apoptotic pathway.
Human and Animal Cells The anti-apoptotic role of the unfolded protein response in Bcr-Abl-positive leukemia cells.
Mice B6.Cg-Tg(Tec-p210 BCR/ABL1)1Homy(RBRC02339) NADPH oxidases as therapeutic targets in chronic myelogenous leukemia.