• 6 Hits
  • 検索条件 : 絞込み (MeSH = Gefitinib / pharmacology)
生物種 リソース名 タイトル
ヒト・動物細胞 PC-9(RCB4455) Heterogeneity among tumors with acquired resistance to EGFR tyrosine kinase inhibitors harboring EGFR-T790M mutation in non-small cell lung cancer cells.
線虫 tm2526 , tm2518 Rab8 and Rabin8-Mediated Tumor Formation by Hyperactivated EGFR Signaling via FGFR Signaling.
ヒト・動物細胞 PC-9(RCB4455) Resminostat, a histone deacetylase inhibitor, circumvents tolerance to EGFR inhibitors in EGFR-mutated lung cancer cells with BIM deletion polymorphism.
実験動物マウス RBRC02759 PLK1 (polo like kinase 1)-dependent autophagy facilitates gefitinib-induced hepatotoxicity by degrading COX6A1 (cytochrome c oxidase subunit 6A1).
ヒト・動物細胞 TE-10(RCB2099) Uptake of collagen type I via macropinocytosis cause mTOR activation and anti-cancer drug resistance.
遺伝子材料 pENTR4-H1 (RDB04395) , CS-RfA-EG (RDB04391) , CSII-CMV-RfA-IRES2-Venus (RDB04388) , pCMV-VSV-G-RSV-Rev (RDB04393) , pCAG-HIVgp (RDB04394). CD200-positive cancer associated fibroblasts augment the sensitivity of Epidermal Growth Factor Receptor mutation-positive lung adenocarcinomas to EGFR Tyrosine kinase inhibitors.