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  • Search Condition : Filter (MeSH = Gene Silencing)
Species Resource
Zebrafish ? A SNF2-like protein facilitates dynamic control of DNA methylation.
Rats W/Kyo(strainID=13) A critical role of TRPM2 in neuronal cell death by hydrogen peroxide.
Arabidopsis / Cultured plant cells, genes pst18173 Folate salvage in plants: pterin aldehyde reduction is mediated by multiple non-specific aldehyde reductases.
Human and Animal Cells PC-14 , LC-1/sq , Lu-134-A , Lu-134-B , A549 , HTOA , JHOS-2 , CACO-2 Lysyl oxidase is a tumor suppressor gene inactivated by methylation and loss of heterozygosity in human gastric cancers.
Drosophila 6895R-1 , 6895R-2 In vivo RNA interference analysis reveals an unexpected role for GNBP1 in the defense against Gram-positive bacterial infection in Drosophila adults.
DNA material pCMX-N/RBP-J (R218H) (RDB03022) Notch ligand Delta-like 1 is essential for postnatal arteriogenesis.
Human and Animal Cells Jurkat , MOLT-4 Suppressor of cytokine signalling-1 gene silencing in acute myeloid leukaemia and human haematopoietic cell lines.
Human and Animal Cells COLO 679 , MMAc Silencing of Peroxiredoxin 2 and aberrant methylation of 33 CpG islands in putative promoter regions in human malignant melanomas.
Yeast BY5209(FY833) , BY5210(FY834) , BY5675(W303-1B) , BY611(S288C) , BYP3121(p3121) , BYP3008(p3008) , BYP3009(p3009) , BYP3010(p3010) Chromosome XII context is important for rDNA function in yeast.
Yeast genomic DNA library Inactivation of the pre-mRNA cleavage and polyadenylation factor Pfs2 in fission yeast causes lethal cell cycle defects.
C.elegans tm345 , tm1483 , tm705 CeVPS-27 is an endosomal protein required for the molting and the endocytic trafficking of the low-density lipoprotein receptor-related protein 1 in Caenorhabditis elegans.
C.intestinalis / (O.japonicus) Wild C.int RNA interference by expressing short hairpin RNA in the Ciona intestinalis embryo.
Arabidopsis / Cultured plant cells, genes rpc00008  Transient RNAi induction against endogenous genes in Arabidopsis protoplasts using in vitro-prepared double-stranded RNA.
C.elegans tm872 Piwi and piRNAs act upstream of an endogenous siRNA pathway to suppress Tc3 transposon mobility in the Caenorhabditis elegans germline.
Drosophila DGRC#109639 Collapse of germline piRNAs in the absence of Argonaute3 reveals somatic piRNAs in flies.
C.elegans tm872 C. elegans piRNAs mediate the genome-wide surveillance of germline transcripts.
C.elegans tm1624 , tm1414 , tm1200 , tm872 piRNAs initiate an epigenetic memory of nonself RNA in the C. elegans germline.
Arabidopsis / Cultured plant cells, genes pda06900 Interaction between the GROWTH-REGULATING FACTOR and KNOTTED1-LIKE HOMEOBOX families of transcription factors.
Tomato TOMJPF00001 Sterol side chain reductase 2 is a key enzyme in the biosynthesis of cholesterol, the common precursor of toxic steroidal glycoalkaloids in potato.
Drosophila DGRC#103877 Drosophila insulin-like peptide-6 (dilp6) expression from fat body extends lifespan and represses secretion of Drosophila insulin-like peptide-2 from the brain.