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  • 11 Hits
  • 検索条件 : 絞込み (MeSH = Huntingtin Protein)
生物種 リソース名 タイトル
ショウジョウバエ Glial cell lineage expression of mutant ataxin-1 and huntingtin induces developmental and late-onset neuronal pathologies in Drosophila models.
ショウジョウバエ Ku70 alleviates neurodegeneration in Drosophila models of Huntington's disease.
ヒト・動物細胞 HCE-T(RCB2280) Lacritin rescues stressed epithelia via rapid forkhead box O3 (FOXO3)-associated autophagy that restores metabolism.
実験動物マウス RBRC00806 The regulation of autophagosome dynamics by huntingtin and HAP1 is disrupted by expression of mutant huntingtin, leading to defective cargo degradation.
ショウジョウバエ 7459R-2 Huntington disease arises from a combinatory toxicity of polyglutamine and copper binding.
ショウジョウバエ 1009R-2 , 1009R-3 Puromycin-sensitive aminopeptidase protects against aggregation-prone proteins via autophagy.
線虫 fust-1(tm4439) , pgrn-1(tm985) Reduction of polyglutamine toxicity by TDP-43, FUS and progranulin in Huntington's disease models.
ヒト・動物細胞 COS-7(RCB0539) , HeLa(RCB0007) 80K-H interacts with inositol 1,4,5-trisphosphate (IP3) receptors and regulates IP3-induced calcium release activity.
ショウジョウバエ RNAi screening in Drosophila cells identifies new modifiers of mutant huntingtin aggregation.
線虫 tm1374 Differential contributions of Caenorhabditis elegans histone deacetylases to huntingtin polyglutamine toxicity.
実験動物マウス RBRC00050 Trehalose alleviates polyglutamine-mediated pathology in a mouse model of Huntington disease.