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  • Search Condition : Filter (MeSH = Huntingtin Protein)
Species Resource
Drosophila Glial cell lineage expression of mutant ataxin-1 and huntingtin induces developmental and late-onset neuronal pathologies in Drosophila models.
Drosophila Ku70 alleviates neurodegeneration in Drosophila models of Huntington's disease.
Human and Animal Cells Lacritin rescues stressed epithelia via rapid forkhead box O3 (FOXO3)-associated autophagy that restores metabolism.
Mice GFP-LC3#53(RBRC00806) The regulation of autophagosome dynamics by huntingtin and HAP1 is disrupted by expression of mutant huntingtin, leading to defective cargo degradation.
Drosophila 7459R-2 Huntington disease arises from a combinatory toxicity of polyglutamine and copper binding.
Drosophila 1009R-2 , 1009R-3 Puromycin-sensitive aminopeptidase protects against aggregation-prone proteins via autophagy.
C.elegans fust-1(tm4439) , pgrn-1(tm985) Reduction of polyglutamine toxicity by TDP-43, FUS and progranulin in Huntington's disease models.
Human and Animal Cells COS-7 (RCB0539) 80K-H interacts with inositol 1,4,5-trisphosphate (IP3) receptors and regulates IP3-induced calcium release activity.
Drosophila RNAi screening in Drosophila cells identifies new modifiers of mutant huntingtin aggregation.
C.elegans tm1374 Differential contributions of Caenorhabditis elegans histone deacetylases to huntingtin polyglutamine toxicity.
Mice B6CBA-TgN(HDexon1)62Gpb(RBRC00050) Trehalose alleviates polyglutamine-mediated pathology in a mouse model of Huntington disease.