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  • Search Condition : Filter (MeSH = Huntington Disease / pathology)
Species Resource Title
Drosophila 11144R-3 Downregulation of glial genes involved in synaptic function mitigates Huntington's disease pathogenesis.
Drosophila Transcriptional repression induces a slowly progressive atypical neuronal death associated with changes of YAP isoforms and p73.
C.elegans tm4397 The neuroprotective transcription factor ATF5 is decreased and sequestered into polyglutamine inclusions in Huntington's disease.
Human and Animal Cells COS-7(RCB0539) Polyglutamine expansion mutation yields a pathological epitope linked to nucleation of protein aggregate: determinant of Huntington's disease onset.
C.elegans fust-1(tm4439) , pgrn-1(tm985) Reduction of polyglutamine toxicity by TDP-43, FUS and progranulin in Huntington's disease models.
Mice RBRC00806 A small-molecule scaffold induces autophagy in primary neurons and protects against toxicity in a Huntington disease model.
C.elegans tm1374 Differential contributions of Caenorhabditis elegans histone deacetylases to huntingtin polyglutamine toxicity.