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  • 11 Hits
  • Search Condition : Filter (MeSH = Leukemia, Lymphocytic, Chronic, B-Cell / pathology)
Species Resource Title
Human and Animal Cells StromaNKtert(RCB2350) Targeting the CXCR4 pathway using a novel anti-CXCR4 IgG1 antibody (PF-06747143) in chronic lymphocytic leukemia.
Human and Animal Cells StromaNKtert(RCB2350) AMG-176, an Mcl-1 Antagonist, Shows Preclinical Efficacy in Chronic Lymphocytic Leukemia.
Human and Animal Cells StromaNKtert(RCB2350) Regulation of Mcl-1 expression in context to bone marrow stromal microenvironment in chronic lymphocytic leukemia.
Human and Animal Cells StromaNKtert(RCB2350) Expression of executioner procaspases and their activation by a procaspase-activating compound in chronic lymphocytic leukemia cells.
Human and Animal Cells StromaNKtert(RCB2350) Serine-70 phosphorylated Bcl-2 prevents oxidative stress-induced DNA damage by modulating the mitochondrial redox metabolism.
Human and Animal Cells StromaNKtert(RCB2350) Bruton's tyrosine kinase inhibition increases BCL-2 dependence and enhances sensitivity to venetoclax in chronic lymphocytic leukemia.
Human and Animal Cells UE6E7T-2(RCB2153) Inhibition of BCR signaling using the Syk inhibitor TAK-659 prevents stroma-mediated signaling in chronic lymphocytic leukemia cells.
Human and Animal Cells PKC-β as a therapeutic target in CLL: PKC inhibitor AEB071 demonstrates preclinical activity in CLL.
Human and Animal Cells StromaNKtert(RCB2350) Evaluation of bendamustine in combination with fludarabine in primary chronic lymphocytic leukemia cells.
Human and Animal Cells StromaNKtert(RCB2350) Decreased mitochondrial apoptotic priming underlies stroma-mediated treatment resistance in chronic lymphocytic leukemia.
Human and Animal Cells KUSA-H1(RCB1990) , ST2(RCB0224) , KUM4(RCB2112) Diverse marrow stromal cells protect CLL cells from spontaneous and drug-induced apoptosis: development of a reliable and reproducible system to assess stromal cell adhesion-mediated drug resistance.