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  • 検索条件 : 絞込み (MeSH = Leukemia, Myelogenous, Chronic, BCR-ABL Positive* / drug therapy)
生物種 リソース名 タイトル
ヒト・動物細胞 Ba/F3(RCB0805) Preclinical characterization of TGRX-678, a brain-penetrant allosteric inhibitor of BCR::ABL1.
ヒト・動物細胞 HL60(RCB0041) , U937 , Jurkat Hypoxia-inducible factor 1α inhibitor induces cell death via suppression of BCR-ABL1 and Met expression in BCR-ABL1 tyrosine kinase inhibitor sensitive and resistant chronic myeloid leukemia cells.
ヒト・動物細胞 K562(RCB0027) Asciminib, a novel allosteric inhibitor of BCR-ABL1, shows synergistic effects when used in combination with imatinib with or without drug resistance.
ヒト・動物細胞 Ba/F3(RCB0805) , K562 FL118 Is a Potent Therapeutic Agent against Chronic Myeloid Leukemia Resistant to BCR-ABL Inhibitors through Targeting RNA Helicase DDX5.
ヒト・動物細胞 Rat-1(RCB1830) Targeting Poly(ADP)ribose polymerase in BCR/ABL1-positive cells.
ヒト・動物細胞 Ba/F3(RCB0805) TPEN/TPGS (T2) combo dramatically reduces Philadelphia chromosome-positive pro-lymphoblastic B leukemia in BALB/c mice.