生物種
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リソース名
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RRC ID
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タイトル
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ジャーナル
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公開日
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外部リンク
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ヒト・動物細胞
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LU65(RCB1967)
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78707
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DNA replication stress and mitotic catastrophe mediate sotorasib addiction in KRASG12C-mutant cancer.
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J Biomed Sci |
2023-6-29 |
Pubmed
Full text
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ヒト・動物細胞
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LK-2(RCB1970)
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78706
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Targeting NFE2L2/KEAP1 Mutations in Advanced NSCLC With the TORC1/2 Inhibitor TAK-228.
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J Thorac Oncol |
2023-4-1 |
Pubmed
Full text
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ヒト・動物細胞
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Ba/F3-CL1(RCB4474)
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78592
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Secondary Mutations of the EGFR Gene That Confer Resistance to Mobocertinib in EGFR Exon 20 Insertion.
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J Thorac Oncol |
2024-1-1 |
Pubmed
Full text
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ヒト・動物細胞
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Ba/F3(RCB0805)
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78156
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The complexity of EGFR exon 19 deletion and L858R mutant cells as assessed by proteomics, transcriptomics, and metabolomics.
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Exp Cell Res |
2023-3-1 |
Pubmed
Full text
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ヒト・動物細胞
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A549(RCB0098)
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HCT116(RCB2979)
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77791
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Bisabosqual A: A novel asparagine synthetase inhibitor suppressing the proliferation and migration of human non-small cell lung cancer A549 cells.
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Eur J Pharmacol |
2023-12-5 |
Pubmed
Full text
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ヒト・動物細胞
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EBC-1(RCB1965)
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77552
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Discovery of LAH-1 as potent c-Met inhibitor for the treatment of non-small cell lung cancer.
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J Enzyme Inhib Med Chem |
2023-1-1 |
Pubmed
Full text
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ヒト・動物細胞
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293T(RCB2202)
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76740
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Inhibition of non-homologous end joining mitigates paclitaxel resistance resulting from mitotic slippage in non-small cell lung cancer.
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Cell Cycle |
2023-9-1 |
Pubmed
Full text
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ヒト・動物細胞
,
遺伝子材料
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II-18(RCB2093)
,
tFucci(CA)2/pCSII-EF (RDB15446)
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76706
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L858R emerges as a potential biomarker predicting response of lung cancer models to anti-EGFR antibodies: Comparison of osimertinib vs. cetuximab.
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Cell Rep Med |
2023-8-3 |
Pubmed
Full text
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実験動物マウス
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RBRC09497
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75628
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Tumor-derived semaphorin 4A improves PD-1-blocking antibody efficacy by enhancing CD8+ T cell cytotoxicity and proliferation.
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Sci Adv |
2023-5-19 |
Pubmed
Full text
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ヒト・動物細胞
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PC-14(RCB0446)
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74901
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Suppression of non-small-cell lung cancer A549 tumor growth by an mtDNA mutation-targeting pyrrole-imidazole polyamide-triphenylphosphonium and a senolytic drug.
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Cancer Sci |
2022-4-1 |
Pubmed
Full text
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ヒト・動物細胞
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LC-2/ad(RCB0440)
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74701
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Dual inhibition of BCL2L1 and MCL1 is highly effective against RET fusion-positive or MET exon 14 skipping mutation-positive lung adenocarcinoma cells.
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Biochem Biophys Res Commun |
2022-11-19 |
Pubmed
Full text
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ヒト・動物細胞
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Lu99(RCB1900)
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LU65(RCB1967)
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74511
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Activity of Adagrasib (MRTX849) in Brain Metastases: Preclinical Models and Clinical Data from Patients with KRASG12C-Mutant Non-Small Cell Lung Cancer.
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Clin Cancer Res |
2022-8-2 |
Pubmed
Full text
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酵母
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74180
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Celastrol inhibits lung cancer growth by triggering histone acetylation and acting synergically with HDAC inhibitors.
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Pharmacol Res |
2022-11-1 |
Pubmed
Full text
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ヒト・動物細胞
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Ba/F3(RCB0805)
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74010
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Fibroblast growth factor receptor 3 overexpression mediates ALK inhibitor resistance in ALK-rearranged non-small cell lung cancer.
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Cancer Sci |
2022-11-1 |
Pubmed
Full text
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ヒト・動物細胞
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II-18(RCB2093)
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73644
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Mutant forms of EGFR promote HER2 trafficking through efficient formation of HER2-EGFR heterodimers.
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Lung Cancer |
2023-1-1 |
Pubmed
Full text
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ヒト・動物細胞
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PC-9(RCB4455)
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Jurkat(RCB3052)
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73099
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A fluorogenic probe for predicting treatment response in non-small cell lung cancer with EGFR-activating mutations.
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Nat Commun |
2022-11-14 |
Pubmed
Full text
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ヒト・動物細胞
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Ba/F3(RCB0805)
,
WEHI-3(RCB0035)
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72002
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Foretinib can overcome common on-target resistance mutations after capmatinib/tepotinib treatment in NSCLCs with MET exon 14 skipping mutation.
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J Hematol Oncol |
2022-6-11 |
Pubmed
Full text
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ヒト・動物細胞
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A549(RCB0098)
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71887
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A New 1,2-Naphthoquinone Derivative with Anti-lung Cancer Activity.
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Chem Pharm Bull (Tokyo) |
2022-1-1 |
Pubmed
Full text
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ヒト・動物細胞
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MS-1(RCB0725)
,
Lu-139(RCB0469)
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71807
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Inhibitors of ABCB1 and ABCG2 overcame resistance to topoisomerase inhibitors in small cell lung cancer.
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Thorac Cancer |
2022-8-1 |
Pubmed
Full text
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ヒト・動物細胞
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Ba/F3(RCB0805)
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71806
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Analysis of lorlatinib analogs reveals a roadmap for targeting diverse compound resistance mutations in ALK-positive lung cancer.
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Nat Cancer |
2022-6-1 |
Pubmed
Full text
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