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  • Search Condition : Filter (MeSH = Lysosomes / pathology)
Species Resource Title
Human and Animal Cells KP4(RCB1005) , PK-1(RCB1972) Bromodomain Protein BRD4 Is a Transcriptional Repressor of Autophagy and Lysosomal Function.
Human and Animal Cells MG6(RCB2403) Progranulin regulates lysosomal function and biogenesis through acidification of lysosomes.
Mice RBRC02231 RIPK1 Promotes Energy Sensing by the mTORC1 Pathway.
Drosophila 31935R-3 The Warburg Micro Syndrome-associated Rab3GAP-Rab18 module promotes autolysosome maturation through the Vps34 Complex I.
C.elegans tm1125 , tm2388 C. elegans-based screen identifies lysosome-damaging alkaloids that induce STAT3-dependent lysosomal cell death.
Human and Animal Cells PC-3(RCB2145) Galectin-9 induces atypical ubiquitination leading to cell death in PC-3 prostate cancer cells.
DNA material CS-CA-MCS (RDB05963) Saturated Fatty Acids Undergo Intracellular Crystallization and Activate the NLRP3 Inflammasome in Macrophages.
C.elegans tm703 , tm830 , tm333 , tm688 A Caenorhabditis elegans model of orotic aciduria reveals enlarged lysosome-related organelles in embryos lacking umps-1 function.
C.elegans tm3767 , tm1693 , tm1877 , tm1447 An AGEF-1/Arf GTPase/AP-1 ensemble antagonizes LET-23 EGFR basolateral localization and signaling during C. elegans vulva induction.
Human and Animal Cells A549 Clathrin-dependent endocytosis of claudin-2 by DFYSP peptide causes lysosomal damage in lung adenocarcinoma A549 cells.
DNA material pCAG-HIVgp (RDB04394) , pCMV-VSV-G-RSV-Rev (RDB04393) NLRP4 negatively regulates autophagic processes through an association with beclin1.
Mice RBRC00806 Impaired turnover of autophagolysosomes in cathepsin L deficiency.