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  • 76 Hits
  • Search Condition : Filter (MeSH = MAP Kinase Signaling System / drug effects)
Species Resource Title
Human and Animal Cells ATDC5(RCB0565) Suppression of cartilage degeneration by intra-articular injection of heparan sulfate 6-O endosulfatase in a mouse osteoarthritis model.
Human and Animal Cells HL60(RCB0041) , U-937 DE-4(RCB0435) Nitrogen-containing bisphosphonates induce apoptosis of hematopoietic tumor cells via inhibition of Ras signaling pathways and Bim-mediated activation of the intrinsic apoptotic pathway.
Human and Animal Cells TKKK(RCB1907) , TGBC2TKB(RCB1130) , TGBC18TKB(RCB1169) , TGBC14TKB(RCB1186) , G-415(RCB2640) , HuCCT1(RCB1960) K-Ras mutation and amplification status is predictive of resistance and high basal pAKT is predictive of sensitivity to everolimus in biliary tract cancer cell lines.
Human and Animal Cells MKN45(RCB1001) In Vitro and In Vivo Activity of AMG 337, a Potent and Selective MET Kinase Inhibitor, in MET-Dependent Cancer Models.
Human and Animal Cells MG6(RCB2403) Ferulic acid suppresses expression of tryptophan metabolic key enzyme indoleamine 2, 3-dioxygenase via NFκB and p38 MAPK in lipopolysaccharide-stimulated microglial cells.
Human and Animal Cells ATDC5(RCB0565) Endogenous cannabinoid anandamide impairs cell growth and induces apoptosis in chondrocytes.
Human and Animal Cells ST2(RCB0224) Bisphosphonate- and statin-induced enhancement of OPG expression and inhibition of CD9, M-CSF, and RANKL expressions via inhibition of the Ras/MEK/ERK pathway and activation of p38MAPK in mouse bone marrow stromal cell line ST2.
Human and Animal Cells KP4(RCB1005) Synthetic Lethal Interaction of SHOC2 Depletion with MEK Inhibition in RAS-Driven Cancers.
Human and Animal Cells MC3T3-E1(RCB1126) Select polyphenolic fractions from dried plum enhance osteoblast activity through BMP-2 signaling.
Human and Animal Cells RAW 264(RCB0535) Terminalia bellirica (Gaertn.) Roxb. Extract and Gallic Acid Attenuate LPS-Induced Inflammation and Oxidative Stress via MAPK/NF-κB and Akt/AMPK/Nrf2 Pathways.
Human and Animal Cells MC3T3-E1(RCB1126) JNK inactivation suppresses osteogenic differentiation, but robustly induces osteopontin expression in osteoblasts through the induction of inhibitor of DNA binding 4 (Id4).
Human and Animal Cells Sa3(RCB0980) , SAS(RCB1974) Growth suppression of human oral cancer cells by candidate agents for cetuximab-side effects.
Human and Animal Cells HSC-2(RCB1945) Nicotine exposure induces the proliferation of oral cancer cells through the α7 subunit of the nicotinic acetylcholine receptor.
Human and Animal Cells 293(RCB1637) Upregulation of transient receptor potential melastatin 6 channel expression by rosiglitazone and all-trans-retinoic acid in erlotinib-treated renal tubular epithelial cells.
Human and Animal Cells C2C12(RCB0987) Granulocyte-colony stimulating factor enhances load-induced muscle hypertrophy in mice.
DNA material phRIT2 (RDB16941) , CSII-CMV-MCS-IRES2-Venus (RDB04383) , pCAG-HIVgp (RDB04394) , pCMV-VSV-G-RSV-Rev (RDB04393) In silico drug screening by using genome-wide association study data repurposed dabrafenib, an anti-melanoma drug, for Parkinson's disease.
C.elegans tm3476 , tm3859 Promotion of behavior and neuronal function by reactive oxygen species in C. elegans.
Human and Animal Cells C2C12(RCB0987) Lactoferrin promotes murine C2C12 myoblast proliferation and differentiation and myotube hypertrophy.
Human and Animal Cells RBE(RCB1292) , YSCCC(RCB1549) Survival pathway of cholangiocarcinoma via AKT/mTOR signaling to escape RAF/MEK/ERK pathway inhibition by sorafenib.
Human and Animal Cells THP-1 (RCB1189) Fluoroquinolones and propionic acid derivatives induce inflammatory responses in vitro.