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  • 89 Hits
  • Search Condition : Filter (MeSH = MAP Kinase Signaling System / drug effects)
Species Resource Title
Human and Animal Cells HTC/C3(RCB0452) Inhibition of IRAK1/4 enhances the antitumor effect of lenvatinib in anaplastic thyroid cancer cells.
Human and Animal Cells PC-12(RCB0009) Luteolin enhances cholinergic activities in PC12 cells through ERK1/2 and PI3K/Akt pathways.
Human and Animal Cells TE-1(RCB2100) , TE-4(RCB2097) , TE-5(RCB1949) , TE-14(RCB2101) , PC-9(RCB4455) Inhibition of mitogen-activated protein kinase pathway can induce upregulation of human leukocyte antigen class I without PD-L1-upregulation in contrast to interferon-γ treatment.
Human and Animal Cells iPSC line Differential coupling of self-renewal signaling pathways in murine induced pluripotent stem cells.
Human and Animal Cells PC-12(RCB0009) Induction of neurite outgrowth in PC12 cells by alpha -phenyl-N-tert-butylnitron through activation of protein kinase C and the Ras-extracellular signal-regulated kinase pathway.
Human and Animal Cells IEC 6(RCB0993) Hydrogen sulfide suppresses the proliferation of intestinal epithelial cells through cell cycle arrest.
Human and Animal Cells COLO205(RCB2127) , COLO-320(RCB1193) , CW-2(RCB0778) , HCT116(RCB2979) Early response in phosphorylation of ribosomal protein S6 is associated with sensitivity to trametinib in colorectal cancer cells.
Human and Animal Cells Colon-26(RCB2657) Orally Administered Mucolytic Drug l-Carbocisteine Inhibits Angiogenesis and Tumor Growth in Mice.
Human and Animal Cells HSC-2(RCB1945) ERK-dependent IL-6 autocrine signaling mediates adaptive resistance to pan-PI3K inhibitor BKM120 in head and neck squamous cell carcinoma.
Human and Animal Cells MH7A(RCB1512) Anti-angiogenic effect of Shikonin in rheumatoid arthritis by downregulating PI3K/AKT and MAPKs signaling pathways.
Human and Animal Cells RAW 264(RCB0535) IL-15 and RANKL Play a Synergistically Important Role in Osteoclastogenesis.
Human and Animal Cells MH7A(RCB1512) The JNK pathway represents a novel target in the treatment of rheumatoid arthritis through the suppression of MMP-3.
Human and Animal Cells A431(RCB0202) Redox cycling of 9,10-phenanthrenequinone activates epidermal growth factor receptor signaling through S-oxidation of protein tyrosine phosphatase 1B.
Human and Animal Cells 10T1/2(RCB0247) Borax induces osteogenesis by stimulating NaBC1 transporter via activation of BMP pathway.
Human and Animal Cells MG6(RCB2403) Hp-s1 Ganglioside Suppresses Proinflammatory Responses by Inhibiting MyD88-Dependent NF-κB and JNK/p38 MAPK Pathways in Lipopolysaccharide-Stimulated Microglial Cells.
Human and Animal Cells FM3A(RCB0086) β-Estradiol Enhanced Secretion of Lipoprotein Lipase from Mouse Mammary Tumor FM3A Cells.
Human and Animal Cells MC3T3-E1(RCB1126) Dual Therapeutic Action of a Neutralizing Anti-FGF2 Aptamer in Bone Disease and Bone Cancer Pain.
Human and Animal Cells ATDC5(RCB0565) Suppression of cartilage degeneration by intra-articular injection of heparan sulfate 6-O endosulfatase in a mouse osteoarthritis model.
Human and Animal Cells HL60(RCB0041) , U-937 DE-4(RCB0435) Nitrogen-containing bisphosphonates induce apoptosis of hematopoietic tumor cells via inhibition of Ras signaling pathways and Bim-mediated activation of the intrinsic apoptotic pathway.
Human and Animal Cells TKKK(RCB1907) , TGBC2TKB(RCB1130) , TGBC18TKB(RCB1169) , TGBC14TKB(RCB1186) , G-415(RCB2640) , HuCCT1(RCB1960) K-Ras mutation and amplification status is predictive of resistance and high basal pAKT is predictive of sensitivity to everolimus in biliary tract cancer cell lines.