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  • Search Condition : Filter (MeSH = MAP Kinase Signaling System / drug effects)
Species Resource
Yeast genomic library Response of fission yeast to toxic cations involves cooperative action of the stress-activated protein kinase Spc1/Sty1 and the Hal4 protein kinase.
Human embryonic stem cells KhES-1 , KhES-3 Defining early lineage specification of human embryonic stem cells by the orchestrated balance of canonical Wnt/beta-catenin, Activin/Nodal and BMP signaling.
DNA material pZRmERK2 (RDB01796) alpha-Synuclein forms a complex with transcription factor Elk-1.
C.elegans Promotion of behavior and neuronal function by reactive oxygen species in C. elegans.
Zebrafish ko095/fli1:EGFP Haemodynamically dependent valvulogenesis of zebrafish heart is mediated by flow-dependent expression of miR-21.
C.elegans tm5011 , tm3860 , tm6254 Endocannabinoid signaling regulates regenerative axon navigation in Caenorhabditis elegans via the GPCRs NPR-19 and NPR-32.
Mice PROD-Cacna1a<tg-rol>/NemOdaRbrc(RBRC00388) Analysis of the protective effects of the α2/δ subunit of voltage-gated Ca2+ channels in brain injury.
Xenopus tropicalis Transgenic Xenopus with prx1 limb enhancer reveals crucial contribution of MEK/ERK and PI3K/AKT pathways in blastema formation during limb regeneration.
General Microbes JCM 6425 , JCM 6473 Glucocorticoids enhance Toll-like receptor 2 expression in human keratinocytes stimulated with Propionibacterium acnes or proinflammatory cytokines.
DNA material pGL4-phSESN2 (RDB07413) Isorhamnetin protects against oxidative stress by activating Nrf2 and inducing the expression of its target genes.
Drosophila Development of biomarker for detecting silver nanoparticles exposure using a GAL4 enhancer trap screening in Drosophila.
Human and Animal Cells THP-1 (RCB1189) Fluoroquinolones and propionic acid derivatives induce inflammatory responses in vitro.
Human and Animal Cells RBE(RCB1292) , YSCCC(RCB1549) Survival pathway of cholangiocarcinoma via AKT/mTOR signaling to escape RAF/MEK/ERK pathway inhibition by sorafenib.
Human and Animal Cells C2C12(RCB0987) Lactoferrin promotes murine C2C12 myoblast proliferation and differentiation and myotube hypertrophy.
Human and Animal Cells C2C12(RCB0987) Granulocyte-colony stimulating factor enhances load-induced muscle hypertrophy in mice.
Human and Animal Cells HSC-2(RCB1945) Nicotine exposure induces the proliferation of oral cancer cells through the α7 subunit of the nicotinic acetylcholine receptor.
Human and Animal Cells Macropinocytosis and TAK1 mediate anti-inflammatory to pro-inflammatory macrophage differentiation by HIV-1 Nef.
Human and Animal Cells Anti-inflammatory effect of pyroglutamyl-leucine on lipopolysaccharide-stimulated RAW 264.7 macrophages.
Human and Animal Cells Naringenin suppresses macrophage infiltration into adipose tissue in an early phase of high-fat diet-induced obesity.
Human and Animal Cells RMS-YM (RCB1695) C-type natriuretic peptide in combination with sildenafil attenuates proliferation of rhabdomyosarcoma cells.