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  • Search Condition : Filter (MeSH = Metformin / pharmacology)
Species Resource Title
Mice RBRC05765 Homeostatic control of nuclear-encoded mitochondrial gene expression by the histone variant H2A.Z is essential for neuronal survival.
Human and Animal Cells HCT116(RCB2979) , DU145(RCB2143) , LNCap.FGC(RCB2144) , B16F10(RCB2630) Petasin potently inhibits mitochondrial complex I-based metabolism that supports tumor growth and metastasis.
Human and Animal Cells RAW 264(RCB0535) Metformin directly binds the alarmin HMGB1 and inhibits its proinflammatory activity.
Mice RBRC02231 RIPK1 Promotes Energy Sensing by the mTORC1 Pathway.
Human and Animal Cells Sawano(RCB1152) The roles of tricellular tight junction protein lipolysis-stimulated lipoprotein receptor in malignancy of human endometrial cancer cells.
Human and Animal Cells PANC-1(RCB2095) , MIA Paca2(RCB2094) Metformin inhibits TGF‑β1‑induced epithelial‑mesenchymal transition and liver metastasis of pancreatic cancer cells.
C.elegans tm1133 , tm1108 Host-Microbe-Drug-Nutrient Screen Identifies Bacterial Effectors of Metformin Therapy.
Human and Animal Cells Hep G2(RCB1886) Metformin Regulates the Expression of CD133 Through the AMPK-CEBPβ Pathway in Hepatocellular Carcinoma Cell Lines.
Human and Animal Cells MKN1(RCB1003) , MKN45(RCB1001) , Kato III(RCB2088) The Antitumor Effects of Metformin on Gastric Cancer In Vitro and on Peritoneal Metastasis.
C.elegans tm2182 AMP-Activated Protein Kinase Regulates Oxidative Metabolism in Caenorhabditis elegans through the NHR-49 and MDT-15 Transcriptional Regulators.
Human and Animal Cells HeLa/Fucci(RCB2812) NOTCH1 Inhibits Activation of ATM by Impairing the Formation of an ATM-FOXO3a-KAT5/Tip60 Complex.
Human and Animal Cells ATDC5(RCB0565) AMP-activated protein kinase (AMPK) activity negatively regulates chondrogenic differentiation.
Silkworms Diabetic silkworms for evaluation of therapeutically effective drugs against type II diabetes.
Human and Animal Cells MC3T3-E1(RCB1126) Osteoblast differentiation is functionally associated with decreased AMP kinase activity.