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15 Hits
Search Condition : Filter (MeSH = Metformin / pharmacology)
Species
Resource
RRC ID
Title
Journal
Published
Link
Human and Animal Cells
Hep G2(RCB1648)
81906
An antifibrotic compound that ameliorates hyperglycaemia and fat accumulation in cell and HFD mouse models.
Diabetologia
2024-11-1
Pubmed
Full text
Mice
RBRC05765
69992
Homeostatic control of nuclear-encoded mitochondrial gene expression by the histone variant H2A.Z is essential for neuronal survival.
Cell Rep
2021-9-14
Pubmed
Full text
Human and Animal Cells
HCT116(RCB2979)
,
DU145(RCB2143)
,
LNCap.FGC(RCB2144)
,
B16F10(RCB2630)
68629
Petasin potently inhibits mitochondrial complex I-based metabolism that supports tumor growth and metastasis.
J Clin Invest
2021-9-1
Pubmed
Full text
Human and Animal Cells
RAW 264(RCB0535)
65055
Metformin directly binds the alarmin HMGB1 and inhibits its proinflammatory activity.
J Biol Chem
2017-5-19
Pubmed
Full text
Mice
RBRC02231
64006
RIPK1 Promotes Energy Sensing by the mTORC1 Pathway.
Mol Cell
2021-1-21
Pubmed
Full text
Human and Animal Cells
Sawano(RCB1152)
63511
The roles of tricellular tight junction protein lipolysis-stimulated lipoprotein receptor in malignancy of human endometrial cancer cells.
Oncotarget
2016-5-10
Pubmed
Full text
Human and Animal Cells
PANC-1(RCB2095)
,
MIA Paca2(RCB2094)
62814
Metformin inhibits TGF‑β1‑induced epithelial‑mesenchymal transition and liver metastasis of pancreatic cancer cells.
Oncol Rep
2020-7-1
Pubmed
Full text
C.elegans
tm1133
,
tm1108
59576
Host-Microbe-Drug-Nutrient Screen Identifies Bacterial Effectors of Metformin Therapy.
Cell
2019-9-5
Pubmed
Full text
Human and Animal Cells
Hep G2(RCB1886)
57773
Metformin Regulates the Expression of CD133 Through the AMPK-CEBPβ Pathway in Hepatocellular Carcinoma Cell Lines.
Neoplasia
2019-6-1
Pubmed
Full text
Human and Animal Cells
MKN1(RCB1003)
,
MKN45(RCB1001)
,
Kato III(RCB2088)
54711
The Antitumor Effects of Metformin on Gastric Cancer
In Vitro
and on Peritoneal Metastasis.
Anticancer Res
2018-11-1
Pubmed
Full text
C.elegans
tm2182
53498
AMP-Activated Protein Kinase Regulates Oxidative Metabolism in Caenorhabditis elegans through the NHR-49 and MDT-15 Transcriptional Regulators.
PLoS One
2016-1-1
Pubmed
Full text
Human and Animal Cells
HeLa/Fucci(RCB2812)
51816
NOTCH1 Inhibits Activation of ATM by Impairing the Formation of an ATM-FOXO3a-KAT5/Tip60 Complex.
Cell Rep
2016-8-23
Pubmed
Full text
Human and Animal Cells
ATDC5(RCB0565)
45407
AMP-activated protein kinase (AMPK) activity negatively regulates chondrogenic differentiation.
Bone
2015-5-1
Pubmed
Full text
Silkworms
36362
Diabetic silkworms for evaluation of therapeutically effective drugs against type II diabetes.
Sci Rep
2015-5-29
Pubmed
Full text
Human and Animal Cells
MC3T3-E1(RCB1126)
19356
Osteoblast differentiation is functionally associated with decreased AMP kinase activity.
J Cell Physiol
2009-12-1
Pubmed
Full text