• 51 Hits
  • Search Condition : Filter (MeSH = Mitogen-Activated Protein Kinase Kinases / metabolism)
Species Resource Title
C.elegans tm3036 , tm3023 , tm13464 , tm2048 Multiple p38/JNK mitogen-activated protein kinase (MAPK) signaling pathways mediate salt chemotaxis learning in C. elegans.
Yeast pGK426(BYP7373), , W303-1B(BY4849) Loss of function of Hog1 improves glycerol assimilation in Saccharomyces cerevisiae.
Zebrafish Tg(EF1a:ERK Biosensor-nes) (teen) Assessment of the FRET-based Teen sensor to monitor ERK activation changes preceding morphological defects in a RASopathy zebrafish model and phenotypic rescue by MEK inhibitor.
Human and Animal Cells 293T(RCB2022) , 293gp(RCB2354) MEK5-ERK5 Axis Promotes Self-renewal and Tumorigenicity of Glioma Stem Cells.
Human and Animal Cells THP-1 Daidzein phosphorylates and activates 5-lipoxygenase via the MEK/ERK pathway: a mechanism for inducing the production of 5-lipoxygenase metabolite that inhibit influenza virus intracellular replication.
Human and Animal Cells CACO-2(RCB0988) , COLO205(RCB2127) p53-armed oncolytic adenovirus induces autophagy and apoptosis in KRAS and BRAF-mutant colorectal cancer cells.
Human and Animal Cells COLO-320(RCB1193) , LoVo(RCB1639) Tumor suppressor miR-193a-3p enhances efficacy of BRAF/MEK inhibitors in BRAF-mutated colorectal cancer.
Yeast A new negative feedback mechanism for MAPK pathway inactivation through Srk1 MAPKAP kinase.
Human and Animal Cells RGM1(RCB0876) Transmural pressure loading enhances gastric mucosal cell proliferation.
Human and Animal Cells 293(RCB1637) , G-361(RCB0991) , A549(RCB3677) , T24(RCB2536) , A431(RCB0202) , PANC-1(RCB2095) , HCT116(RCB2979) , 293gp(RCB2354) Qualitative differences in disease-associated MEK mutants reveal molecular signatures and aberrant signaling-crosstalk in cancer.
Human and Animal Cells COLO205(RCB2127) , COLO-320(RCB1193) , CW-2(RCB0778) , HCT116(RCB2979) Early response in phosphorylation of ribosomal protein S6 is associated with sensitivity to trametinib in colorectal cancer cells.
Human and Animal Cells MC3T3-G2/PA6(RCB1127) Inhibition of FGF10-ERK signal activation suppresses intraductal papillary neoplasm of the bile duct and its associated carcinomas.
Human and Animal Cells Hep G2(RCB1886) Elevated levels of expression of cytochrome P450 3A4 in a human liver epithelial cell line in differentiation-inducing conditions.
Human and Animal Cells OVK18(RCB1903) Reprogramming of Nucleotide Metabolism Mediates Synergy between Epigenetic Therapy and MAP Kinase Inhibition.
Human and Animal Cells OS-RC-2(RCB0735) , TUHR10TKB(RCB1275) , TUHR14TKB(RCB1383) Oncogenic roles of TOPK and MELK, and effective growth suppression by small molecular inhibitors in kidney cancer cells.
Human and Animal Cells MMAc·SF(RCB1200) Receptor-Driven ERK Pulses Reconfigure MAPK Signaling and Enable Persistence of Drug-Adapted BRAF-Mutant Melanoma Cells.
Human and Animal Cells MtT/S(RCB0528) Effect of interleukin-1 beta on growth hormone gene expression and its possible molecular mechanism in rat MtT/S somatotroph cells.
Human and Animal Cells RAW 264(RCB0535) Involvement of p38 mitogen-activated protein kinase signaling pathway in osteoclastogenesis mediated by receptor activator of NF-kappa B ligand (RANKL).
Human and Animal Cells MC3T3-E1(RCB1126) Chemically modified tetracyclines selectively inhibit IL-6 expression in osteoblasts by decreasing mRNA stability.
Clawed frogs / Newts Cdc2-like kinase 2 (Clk2) promotes early neural development in Xenopus embryos.