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  • Search Condition : Filter (MeSH = Mitogen-Activated Protein Kinase Kinases / metabolism)
Species Resource
DNA material AxCALacZ (RDB1745) Galpha12/13-mediated production of reactive oxygen species is critical for angiotensin receptor-induced NFAT activation in cardiac fibroblasts.
C.elegans tm618 , tm1789 Specification of the C. elegans MS blastomere by the T-box factor TBX-35.
Drosophila Egfr/Ras signaling regulates DE-cadherin/Shotgun localization to control vein morphogenesis in the Drosophila wing.
Drosophila 11859R-2 , 3608R-1 , 1954R-1 , 2829R-1 , 32134R-2 p53- and ERK7-dependent ribosome surveillance response regulates Drosophila insulin-like peptide secretion.
Mice B6;129-Grn<tm1>(RBRC02370) Progranulin reduction is associated with increased tau phosphorylation in P301L tau transgenic mice.
Rats Involvement of Ca2+-dependent proteasome in the degradation of both cyclin B1 and Mos during spontaneous activation of matured rat oocytes.
Human and Animal Cells MC3T3-E1 (RCB1126) Fluoride-induced c-Fos expression in MC3T3-E1 osteoblastic cells.
Human and Animal Cells E14tg2a(AES0135) Activin A in combination with ERK1/2 MAPK pathway inhibition sustains propagation of mouse embryonic stem cells.
Human and Animal Cells Regulation of the hedgehog signaling by the mitogen-activated protein kinase cascade in gastric cancer.
Human and Animal Cells PC-12 (RCB0009) Neurite outgrowth mediated by translation elongation factor eEF1A1: a target for antiplatelet agent cilostazol.
Human and Animal Cells Vero-317 (RCB0272) Verots S3 (RCB0707) Medium osmolarity-dependent biosynthesis of renal cellular sulfoglycolipids is mediated by the MAPK signaling pathway.
Human and Animal Cells NB1RGB (RCB0222) Modulation of calprotectin in human keratinocytes by keratinocyte growth factor and interleukin-1alpha.
Human and Animal Cells Y79 (RCB1645) WERI-Rb-1 (RCB2146) Antitumor activity of TMPyP4 interacting G-quadruplex in retinoblastoma cell lines.
Human and Animal Cells Retinoid X receptor alpha is highly phosphorylated in retinoic acid-resistant HL-60R cells and the combination of 9-cis retinoic acid plus MEK inhibitor induces apoptosis in the cells.
Human and Animal Cells A novel molecule 'shati' increases dopamine uptake via the induction of tumor necrosis factor-alpha in pheochromocytoma-12 cells.
Human and Animal Cells KRAS or BRAF mutation status is a useful predictor of sensitivity to MEK inhibition in ovarian cancer.
Human and Animal Cells Glycyrrhizin and isoliquiritigenin suppress the LPS sensor toll-like receptor 4/MD-2 complex signaling in a different manner.
Human and Animal Cells A549 Prostaglandin E2 reinforces the activation of Ras signal pathway in lung adenocarcinoma cells via EP3.
Human and Animal Cells K562 Ectopic cyclin D1 expression blocks STI571-induced erythroid differentiation of K562 cells.
Human and Animal Cells Jurkat A link between benzyl isothiocyanate-induced cell cycle arrest and apoptosis: involvement of mitogen-activated protein kinases in the Bcl-2 phosphorylation.