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  • Search Condition : Filter (MeSH = Mitogen-Activated Protein Kinase Kinases / metabolism)
Species Resource Title
Yeast A new negative feedback mechanism for MAPK pathway inactivation through Srk1 MAPKAP kinase.
Human and Animal Cells RGM1(RCB0876) Transmural pressure loading enhances gastric mucosal cell proliferation.
Human and Animal Cells 293(RCB1637) , G-361(RCB0991) , A549(RCB3677) , T24(RCB2536) , A431(RCB0202) , PANC-1(RCB2095) , HCT116(RCB2979) , 293gp(RCB2354) Qualitative differences in disease-associated MEK mutants reveal molecular signatures and aberrant signaling-crosstalk in cancer.
Human and Animal Cells COLO205(RCB2127) , COLO-320(RCB1193) , CW-2(RCB0778) , HCT116(RCB2979) Early response in phosphorylation of ribosomal protein S6 is associated with sensitivity to trametinib in colorectal cancer cells.
Human and Animal Cells MC3T3-G2/PA6(RCB1127) Inhibition of FGF10-ERK signal activation suppresses intraductal papillary neoplasm of the bile duct and its associated carcinomas.
Human and Animal Cells Hep G2(RCB1886) Elevated levels of expression of cytochrome P450 3A4 in a human liver epithelial cell line in differentiation-inducing conditions.
Human and Animal Cells OVK18(RCB1903) Reprogramming of Nucleotide Metabolism Mediates Synergy between Epigenetic Therapy and MAP Kinase Inhibition.
Human and Animal Cells OS-RC-2(RCB0735) , TUHR10TKB(RCB1275) , TUHR14TKB(RCB1383) Oncogenic roles of TOPK and MELK, and effective growth suppression by small molecular inhibitors in kidney cancer cells.
Human and Animal Cells MMAc·SF(RCB1200) Receptor-Driven ERK Pulses Reconfigure MAPK Signaling and Enable Persistence of Drug-Adapted BRAF-Mutant Melanoma Cells.
Human and Animal Cells MtT/S(RCB0528) Effect of interleukin-1 beta on growth hormone gene expression and its possible molecular mechanism in rat MtT/S somatotroph cells.
Human and Animal Cells RAW 264(RCB0535) Involvement of p38 mitogen-activated protein kinase signaling pathway in osteoclastogenesis mediated by receptor activator of NF-kappa B ligand (RANKL).
Human and Animal Cells MC3T3-E1(RCB1126) Chemically modified tetracyclines selectively inhibit IL-6 expression in osteoblasts by decreasing mRNA stability.
Clawed frogs / Newts Cdc2-like kinase 2 (Clk2) promotes early neural development in Xenopus embryos.
Human and Animal Cells ATDC5(RCB0565) Green tea polyphenols attenuate LPS-induced inflammation through upregulating microRNA-9 in murine chondrogenic ATDC5 cells.
Human and Animal Cells E14tg2a(AES0135) Activin A in combination with ERK1/2 MAPK pathway inhibition sustains propagation of mouse embryonic stem cells.
Human and Animal Cells MC3T3-E1(RCB1126) Fluoride-induced c-Fos expression in MC3T3-E1 osteoblastic cells.
Human and Animal Cells RAW 264(RCB0535) Glycyrrhizin and isoliquiritigenin suppress the LPS sensor toll-like receptor 4/MD-2 complex signaling in a different manner.
Human and Animal Cells OMC-3(RCB0755) , JHOC-5(RCB1520) KRAS or BRAF mutation status is a useful predictor of sensitivity to MEK inhibition in ovarian cancer.
Human and Animal Cells PC-12(RCB0009) A novel molecule 'shati' increases dopamine uptake via the induction of tumor necrosis factor-alpha in pheochromocytoma-12 cells.
Human and Animal Cells Retinoid X receptor alpha is highly phosphorylated in retinoic acid-resistant HL-60R cells and the combination of 9-cis retinoic acid plus MEK inhibitor induces apoptosis in the cells.