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  • 17 Hits
  • Search Condition : Filter (MeSH = Motor Neurons / pathology)
Species Resource Title
Mice RBRCGD000108 , RBRCGD000110 Mice with endogenous TDP-43 mutations exhibit gain of splicing function and characteristics of amyotrophic lateral sclerosis.
Human and Animal Cells 409B2(HPS0076) A widespread family of heat-resistant obscure (Hero) proteins protect against protein instability and aggregation.
C.elegans tm700 Disruption of genes associated with Charcot-Marie-Tooth type 2 lead to common behavioural, cellular and molecular defects in Caenorhabditis elegans.
Zebrafish Tg(isl1:GFP)rw0 Exosc2 deficiency leads to developmental disorders by causing a nucleotide pool imbalance in zebrafish.
Zebrafish Tg(HuC:GVP) Myelin degeneration induced by mutant superoxide dismutase 1 accumulation promotes amyotrophic lateral sclerosis.
Mice RBRC02192 , RBRC05147 Involvement of p38 in Age-Related Decline in Adult Neurogenesis via Modulation of Wnt Signaling.
Drosophila Hippo, Drosophila MST, is a novel modifier of motor neuron degeneration induced by knockdown of Caz, Drosophila FUS.
C.elegans tm1086 The C. elegans BRCA2-ALP/Enigma Complex Regulates Axon Regeneration via a Rho GTPase-ROCK-MLC Phosphorylation Pathway.
C.elegans tm4255 Neuron-specific knock-down of SMN1 causes neuron degeneration and death through an apoptotic mechanism.
Drosophila 6117R-1 , 6117R-2 The PKA-C3 catalytic subunit is required in two pairs of interneurons for successful mating of Drosophila.
Zebrafish Tg(CM-isl1:GFP) Altered RNA metabolism due to a homozygous RBM7 mutation in a patient with spinal motor neuropathy.
DNA material pEF-BOS FLAG-mouse Rab29 (RDB14971) , pEF-BOS FLAG-mouse Rab29-Q67L (RDB14972) , pEF-BOS FLAG-mouse Rab29-T21N (RDB14973). C9orf72 and RAB7L1 regulate vesicle trafficking in amyotrophic lateral sclerosis and frontotemporal dementia.
C.elegans tm2484 Neurodegeneration in C. elegans models of ALS requires TIR-1/Sarm1 immune pathway activation in neurons.
Zebrafish Tg(brn3a-hsp70:GFP)/rw0110b The cellular and molecular progression of mitochondrial dysfunction induced by 2,4-dinitrophenol in developing zebrafish embryos.
Zebrafish Tg(isl1:GFP)/rw0 Early interneuron dysfunction in ALS: insights from a mutant sod1 zebrafish model.
C.elegans tm2815 The function of a spindle checkpoint gene bub-1 in C. elegans development.
Human and Animal Cells GI-1(RCB0763) VEGF is a modifier of amyotrophic lateral sclerosis in mice and humans and protects motoneurons against ischemic death.