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  • Search Condition : Filter (MeSH = Nerve Degeneration / metabolism)
Species Resource Title
C.elegans tm5211 , tm2679 The stress-responsive gene GDPGP1/mcp-1 regulates neuronal glycogen metabolism and survival.
Drosophila Parkinson's disease-associated iPLA2-VIA/PLA2G6 regulates neuronal functions and α-synuclein stability through membrane remodeling.
C.elegans pink-1(tm1779), lrk-1(tm1898) Dysregulation of the Mitochondrial Unfolded Protein Response Induces Non-Apoptotic Dopaminergic Neurodegeneration in C. elegans Models of Parkinson's Disease.
C.elegans tm805 , tm3036 , tm3117 The Apoptotic Engulfment Machinery Regulates Axonal Degeneration in C. elegans Neurons.
C.elegans tm1817 , tm4995 Mutations in Caenorhabditis elegans neuroligin-like glit-1, the apoptosis pathway and the calcium chaperone crt-1 increase dopaminergic neurodegeneration after 6-OHDA treatment.
C.elegans tm1346 , tm918 Activation of the mitochondrial unfolded protein response promotes longevity and dopamine neuron survival in Parkinson's disease models.
C.elegans tm1779 , tm1898 , tm598 Dysregulation of the Mitochondrial Unfolded Protein Response Induces Non-Apoptotic Dopaminergic Neurodegeneration in C. elegans Models of Parkinson's Disease.
DNA material CSII-CMV-Venus-Mito-IRES2-Bsd (RDB08118) , CS-CDF-CG-PRE (RDB04379). Elavl3 is essential for the maintenance of Purkinje neuron axons.
C.elegans tm1961 , tm474 Caenorhabditis elegans as an experimental tool for the study of complex neurological diseases: Parkinson's disease, Alzheimer's disease and autism spectrum disorder.
Zebrafish Tg(huC:GVP)   Induction of clusterin expression by neuronal cell death in Zebrafish.
Human and Animal Cells NB2a(RCB2639) DJ-1 forms complexes with mutant SOD1 and ameliorates its toxicity.
Drosophila , DNA material pUAST-dFoxO (RDB07961) , pBluescriptSKII(+)-dFoxO (RDB07960) Activation of FoxO by LRRK2 induces expression of proapoptotic proteins and alters survival of postmitotic dopaminergic neuron in Drosophila.
Drosophila 7459R-2 Inhibition of human high-affinity copper importer Ctr1 orthologous in the nervous system of Drosophila ameliorates Aβ42-induced Alzheimer's disease-like symptoms.
Medaka Kyoto-cab (OK-Cab (MT830)) A chemical neurotoxin, MPTP induces Parkinson's disease like phenotype, movement disorders and persistent loss of dopamine neurons in medaka fish.
Drosophila Protein transduction domain-mediated delivery of QBP1 suppresses polyglutamine-induced neurodegeneration in vivo.
C.elegans tm690 , tm858 , tm818 Caenorhabditis elegans glutamate transporter deletion induces AMPA-receptor/adenylyl cyclase 9-dependent excitotoxicity.
C.elegans tm1374 Differential contributions of Caenorhabditis elegans histone deacetylases to huntingtin polyglutamine toxicity.