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  • 検索条件 : 絞込み (MeSH = Protein Aggregation, Pathological / metabolism*)
生物種 リソース名 タイトル
ショウジョウバエ Disulfide bond formation in microtubule-associated tau protein promotes tau accumulation and toxicity in vivo.
線虫 tm5210 Reduction of WDR81 impairs autophagic clearance of aggregated proteins and cell viability in neurodegenerative phenotypes.
線虫 Loss of glutathione redox homeostasis impairs proteostasis by inhibiting autophagy-dependent protein degradation.
遺伝子材料 pCAG-HIVgp (RDB04394) , pCMV-VSV-G (RDB04392) TAR DNA-Binding Protein 43 and Disrupted in Schizophrenia 1 Coaggregation Disrupts Dendritic Local Translation and Mental Function in Frontotemporal Lobar Degeneration.
ショウジョウバエ 8439R-1 , 8439R-4 CCT complex restricts neuropathogenic protein aggregation via autophagy.
ショウジョウバエ 5680R-2 Quantification of Ataxin-3 and Ataxin-7 aggregates formed in vivo in Drosophila reveals a threshold of aggregated polyglutamine proteins associated with cellular toxicity.
遺伝子材料 IRAL010J08 (HGY084224) Aggregation of ALS-linked FUS mutant sequesters RNA binding proteins and impairs RNA granules formation.