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  • Search Condition : Filter (MeSH = Protein Aggregation, Pathological / metabolism*)
Species Resource Title
Drosophila Disulfide bond formation in microtubule-associated tau protein promotes tau accumulation and toxicity in vivo.
C.elegans tm5210 Reduction of WDR81 impairs autophagic clearance of aggregated proteins and cell viability in neurodegenerative phenotypes.
C.elegans Loss of glutathione redox homeostasis impairs proteostasis by inhibiting autophagy-dependent protein degradation.
DNA material pCAG-HIVgp (RDB04394) , pCMV-VSV-G (RDB04392) TAR DNA-Binding Protein 43 and Disrupted in Schizophrenia 1 Coaggregation Disrupts Dendritic Local Translation and Mental Function in Frontotemporal Lobar Degeneration.
Drosophila 8439R-1 , 8439R-4 CCT complex restricts neuropathogenic protein aggregation via autophagy.
Drosophila 5680R-2 Quantification of Ataxin-3 and Ataxin-7 aggregates formed in vivo in Drosophila reveals a threshold of aggregated polyglutamine proteins associated with cellular toxicity.
DNA material IRAL010J08 (HGY084224) Aggregation of ALS-linked FUS mutant sequesters RNA binding proteins and impairs RNA granules formation.