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  • 検索条件 : 絞込み (MeSH = Protein Tyrosine Phosphatase, Non-Receptor Type 11 / metabolism*)
生物種 リソース名 RRC ID タイトル ジャーナル 公開日 外部リンク
実験動物マウス RBRC02142 88485 PD-L2 suppresses T cell signaling via coinhibitory microcluster formation and SHP2 phosphatase recruitment. Commun Biol 2021-5-14 Pubmed Full text
ヒト・動物細胞 HCE-T(RCB2280) 72244 High-risk neuroblastoma with NF1 loss of function is targetable using SHP2 inhibition. Cell Rep 2022-7-26 Pubmed Full text
ヒト・動物細胞 MC3T3-E1(RCB1126) 44693 IL-6 negatively regulates osteoblast differentiation through the SHP2/MEK2 and SHP2/Akt2 pathways in vitro. J Bone Miner Metab 2014-7-1 Pubmed Full text
遺伝子材料 8xGT-IIC-LucII (RDB08067) , pcDNA3.1-pA83-HA-Yap (RDB12190) , pcDNA3.1-pA83-Lats2 (RDB12200) 28591 YAP and TAZ, Hippo signaling targets, act as a rheostat for nuclear SHP2 function. Dev Cell 2013-9-30 Pubmed Full text
実験動物マウス RBRC02142 17572 Programmed cell death 1 forms negative costimulatory microclusters that directly inhibit T cell receptor signaling by recruiting phosphatase SHP2. J Exp Med 2012-6-4 Pubmed Full text
遺伝子材料 pCMV-VSV-G-RSV-Rev (RDB04393) 12765 G-CSF receptor activation of the Src kinase Lyn is mediated by Gab2 recruitment of the Shp2 phosphatase. Blood 2011-7-28 Pubmed Full text
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