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  • Search Condition : Filter (MeSH = Protein-Arginine N-Methyltransferases / metabolism)
Species Resource Title
DNA material pCMFlag_hsSMAD3 (RDB07019) Fibroblast-specific PRMT5 deficiency suppresses cardiac fibrosis and left ventricular dysfunction in male mice.
Human and Animal Cells SAS(RCB1974) , 293gp(RCB2354) Inhibition of PRMT5/MEP50 Arginine Methyltransferase Activity Causes Cancer Vulnerability in NDRG2low Adult T-Cell Leukemia/Lymphoma.
Zebrafish UAS:GFP Prmt5 promotes vascular morphogenesis independently of its methyltransferase activity.
Human and Animal Cells 293T(RCB2202) FBXO11 constitutes a major negative regulator of MHC class II through ubiquitin-dependent proteasomal degradation of CIITA.
Human and Animal Cells TE-11(RCB2100) Arginine methylation of MTHFD1 by PRMT5 enhances anoikis resistance and cancer metastasis.
Human and Animal Cells Lu99(RCB1900) Fragment-Based Discovery of MRTX1719, a Synthetic Lethal Inhibitor of the PRMT5•MTA Complex for the Treatment of MTAP-Deleted Cancers.
DNA material pCAG-HIVgp (RDB04394) , pCMV-VSV-G-RSV-Rev (RDB04393) , CS-RfA-CG (RDB04390) , pENTR4-H1 (RDB04395) 5-Hydroxymethylcytosine plays a critical role in glioblastomagenesis by recruiting the CHTOP-methylosome complex.
Human and Animal Cells PK-59(RCB1901) PRMT1-dependent regulation of RNA metabolism and DNA damage response sustains pancreatic ductal adenocarcinoma.
Human and Animal Cells ST2(RCB0224) PRMT5 inhibition promotes osteogenic differentiation of mesenchymal stromal cells and represses basal interferon stimulated gene expression.
Drosophila 9882R-1 , 9882R-3 Sm protein methylation is dispensable for snRNP assembly in Drosophila melanogaster.