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Species Resource Title
Yeast BYP1806 Acquired resistance to severe ethanol stress-induced inhibition of proteasomal proteolysis in Saccharomyces cerevisiae.
Human and Animal Cells HCT116(RCB2979) Lenalidomide derivatives and proteolysis-targeting chimeras for controlling neosubstrate degradation.
Mice RBRC10149 Overexpression of Nfe2l1 increases proteasome activity and delays vision loss in a preclinical model of human blindness.
Human and Animal Cells HuH-7(RCB1366) , HCT116(RCB2979) Alpha 2-macroglobulin acts as a clearance factor in the lysosomal degradation of extracellular misfolded proteins.
C.elegans tm2371 , tm4791 , tm445 , tm1888 , tm2560 , tm544 Thermosensation in Caenorhabditis elegans is linked to ubiquitin-dependent protein turnover via insulin and calcineurin signalling.
C.elegans tm5159 , tm2081 Endocytosis in the axon initial segment maintains neuronal polarity.
C.elegans tm598 LONP-1 and ATFS-1 sustain deleterious heteroplasmy by promoting mtDNA replication in dysfunctional mitochondria.
C.elegans tm1595 , tm5356 , tm847 , tm2423 , tm2404 , tm3643 , tm1320 SNX-3 mediates retromer-independent tubular endosomal recycling by opposing EEA-1-facilitated trafficking.
C.elegans tm2469 The auxin-inducible degron 2 (AID2) system enables controlled protein knockdown during embryogenesis and development in Caenorhabditis elegans.
C.elegans tm1448 Neuronal postdevelopmentally acting SAX-7S/L1CAM can function as cleaved fragments to maintain neuronal architecture in Caenorhabditis elegans.
General Microbes JCM 14859 , JCM 14860 , JCM 13464 , JCM 13449 , JCM 13469 , JCM 14966 Identification of trypsin-degrading commensals in the large intestine.
Yeast Dual roles of yeast Rad51 N-terminal domain in repairing DNA double-strand breaks.
Silkworms Antheraea pernyi , Antheraea yamamai , Saturnia jonasii, , Actias aliena , Aglia japonica (Saturniidae) Limited proteolysis by a prostatic endopeptidase, the sperm-activating factor initiatorin, regulates the activation of pro-carboxypeptidase B in the seminal fluid of the silkworm, Bombyx mori.
DNA material pCW57-CMV-ssRFP-GFP-KDEL (RDB19767) , pMRX-INU-FLAG-RTN3L (RDB19781) Intrinsically Disordered Protein TEX264 Mediates ER-phagy.
Yeast FY33599 , FY33600 , FY33601 , FY33603 , FY21102 , FY21103 , FY21104 , FY39919 , FY39920 , FY39921 An improved auxin-inducible degron system for fission yeast.
Human and Animal Cells HeLa(RCB0007) A MicroRNA Derived from Adenovirus Virus-Associated RNAII Promotes Virus Infection via Posttranscriptional Gene Silencing.
Drosophila DGRC#107554 , DGRC#101586 , 6343R-1 , 6343R-2 , 2286R-2 The Nrf2-Keap1 pathway is activated by steroid hormone signaling to govern neuronal remodeling.
Drosophila DGRC#115622 , DGRC#115336 Drosophila p38 MAPK interacts with BAG-3/starvin to regulate age-dependent protein homeostasis.
Drosophila DGRC#115622 , DGRC#115336 Drosophila p38 MAPK interacts with BAG-3/starvin to regulate age-dependent protein homeostasis.
Arabidopsis / Cultured plant cells, genes pdx62360 , pdz08478 , pdx62834 Transcriptome, metabolome and suppressor analysis reveal an essential role for the ubiquitin-proteasome system in seedling chloroplast development.