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論文 - 一覧

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  • 検索条件 : 絞込み (MeSH = Proteolysis)
生物種 リソース名 タイトル
ヒト・動物細胞 Hep G2( RCB1648) GPLD1 is a scavenger carrier mediating lysosomal degradation of extracellular aberrant proteins.
原核生物(大腸菌) Periplasmic Serine Protease Prc is Responsible for Amyloid Subunit CsgA Degradation and Proteostasis in Escherichia coli.
原核生物(大腸菌) Membrane-embedded polar residues target membrane proteins for degradation by the quality control protease FtsH.
実験動物マウス RBRC01834 Development of a novel conditional knockdown mouse based on YB-1 protein degradation.
線虫 tm1978 , tm4525 A lysosomal surveillance response to stress extends healthspan.
線虫 tm1146 , tm783 , tm760 Hyperactive 20S proteasome enhances proteostasis and ERAD in C. elegans via degradation of intrinsically disordered proteins.
線虫 tm6026 Identification of presenilin mutations that have sufficient gamma-secretase proteolytic activity to mediate Notch signaling but disrupt organelle and neuronal health.
線虫 tm1133 , tm1968 Inactivation of SIAH-1 E3 ligase attenuates Aβ toxicity by suppressing ubiquitin-dependent DVE-1 degradation in Caenorhabditis elegans models of Alzheimer's disease.
病原細菌 JNBP_31129 , JNBP_30766 Ligand binding drives proteolysis of the SmcR master transcription factor and controls quorum sensing-state transitions in Vibrio species.
ゼブラフィッシュ UAS:GFP-LC3-RFP-LC3∆G, SAGFF(LF)73A, SAIGFF213A, mnr2b-hs:Gal4, TDP-43DKO, UAS:hmCP2AGd410mT436A, UAS:mCherry-P2A-EGFP-d410m-T436A Intrinsically accelerated cellular degradation is amplified by TDP-43 loss in ALS-vulnerable motor neurons in a zebrafish model.
実験動物マウス RBRC01834 ARMC5 selectively degrades SCAP-free SREBF1 and is essential for fatty acid desaturation in adipocytes.
酵母 FY24592 , FY40844 , FY13814 , FY8770 , FY24011 Balance of polo-like kinase Plo1 and monopolar attachment protein 1 (Moa1) regulates fission yeast meiosis.
ヒト・動物細胞 , 遺伝子材料 293T(RCB2202) , CSII-EF-MCS (RDB04378) , pCAG-HIVgp (RDB04394) , pCMV-VSV-G-RSV-Rev (RDB04393) ESCRT-I and PTPN23 mediate microautophagy of ubiquitylated tau aggregates.
ヒト・動物細胞 HuH7 TERT upregulation promotes cell proliferation via degradation of p21 and increases carcinogenic potential.
ショウジョウバエ 6303R-1 , 6303R-2 , 2924R-3 , 4502R-2 , 7656R-2 , 7656R-1 , 8188R-1 , 8188R-2 , 7425R-2 , 7425R-1 , ... The ubiquitin-conjugating enzyme UBE2D maintains a youthful proteome and ensures protein quality control during aging by sustaining proteasome activity.
酵母 The ortholog of human DNAJC9 promotes histone H3-H4 degradation and is counteracted by Asf1 in fission yeast.
酵母 BYP9806 Role of a novel endoplasmic reticulum-resident glycoprotein Mtc6/Ehg2 in high-pressure growth: stability of tryptophan permease Tat2 in Saccharomyces cerevisiae.
遺伝子材料 pCAG-HIVgp (RDB04394) , CS-RfA-CG (RDB04390) , pCMV-VSV-G-RSV-Rev (RDB04393) Long noncoding RNA UPAT promotes colon tumorigenesis by inhibiting degradation of UHRF1.
実験動物マウス RBRC03456 LXN deficiency regulates cytoskeleton remodelling by promoting proteolytic cleavage of Filamin A in vascular endothelial cells.
遺伝子材料 pCI-Neo ADAMTS4(wt)-MH (RDB18693) , pCI-Neo ADAMTS4(3WF)-MH (RDB18694) , pCI-Neo ADAMTS4(WF)-MH (RDB18695) Requirement for C-mannosylation to be secreted and activated a disintegrin and metalloproteinase with thrombospondin motifs 4 (ADAMTS4).