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  • Search Condition : Filter (MeSH = Proteolysis)
Species Resource Title
DNA material pCAG-HIVgp (RDB04394) , CS-RfA-CG (RDB04390) , pCMV-VSV-G-RSV-Rev (RDB04393) Long noncoding RNA UPAT promotes colon tumorigenesis by inhibiting degradation of UHRF1.
Mice RBRC03456 LXN deficiency regulates cytoskeleton remodelling by promoting proteolytic cleavage of Filamin A in vascular endothelial cells.
DNA material pCI-Neo ADAMTS4(wt)-MH (RDB18693) , pCI-Neo ADAMTS4(3WF)-MH (RDB18694) , pCI-Neo ADAMTS4(WF)-MH (RDB18695) Requirement for C-mannosylation to be secreted and activated a disintegrin and metalloproteinase with thrombospondin motifs 4 (ADAMTS4).
Human and Animal Cells NIH3T3-3-4(RCB1862) TRAF7 determines circadian period through ubiquitination and degradation of DBP.
DNA material CSII-CMV-MCS-IRES2-Bsd (RDB04385) , pCMV-VSV-G-RSV-Rev (RDB04393) , pCAG-HIVgp (REB04394) CNKSR1 serves as a scaffold to activate an EGFR phosphatase via exclusive interaction with RhoB-GTP.
Human and Animal Cells RPMI8226(RCB3010) Acceleration of Protein Degradation by 20S Proteasome-Binding Peptides Generated by In Vitro Artificial Evolution.
Yeast BYP1806 Acquired resistance to severe ethanol stress-induced inhibition of proteasomal proteolysis in Saccharomyces cerevisiae.
Human and Animal Cells , DNA material HCT116(RCB2979) , THP-1(RCB368&) , KG-1a(RCB1928) , pCAG-HIVgp (RDB04394) , pCMV-VSV-G-RSV-Rev (RDB04393) Lenalidomide derivatives and proteolysis-targeting chimeras for controlling neosubstrate degradation.
Mice RBRC10149 Overexpression of Nfe2l1 increases proteasome activity and delays vision loss in a preclinical model of human blindness.
Human and Animal Cells , DNA material HuH-7(RCB1366) , HCT116(RCB2979) , HeLa , A549 , pcDNA5 alpha 2M-RFP-GFP-His (RDB20287) , pcDNA5 alpha 2M-ALFA-His (RDB20288) , pcDNA5 alpha 2M-delta bait-RFP-GFP-His (RDB20289) Alpha 2-macroglobulin acts as a clearance factor in the lysosomal degradation of extracellular misfolded proteins.
C.elegans tm2371 , tm4791 , tm445 , tm1888 , tm2560 , tm544 Thermosensation in Caenorhabditis elegans is linked to ubiquitin-dependent protein turnover via insulin and calcineurin signalling.
C.elegans tm5159 , tm2081 Endocytosis in the axon initial segment maintains neuronal polarity.
C.elegans tm598 LONP-1 and ATFS-1 sustain deleterious heteroplasmy by promoting mtDNA replication in dysfunctional mitochondria.
C.elegans tm1595 , tm5356 , tm847 , tm2423 , tm2404 , tm3643 , tm1320 SNX-3 mediates retromer-independent tubular endosomal recycling by opposing EEA-1-facilitated trafficking.
C.elegans tm2469 The auxin-inducible degron 2 (AID2) system enables controlled protein knockdown during embryogenesis and development in Caenorhabditis elegans.
C.elegans tm1448 Neuronal postdevelopmentally acting SAX-7S/L1CAM can function as cleaved fragments to maintain neuronal architecture in Caenorhabditis elegans.
General Microbes JCM 14859 , JCM 14860 , JCM 13464 , JCM 13449 , JCM 13469 , JCM 14966 Identification of trypsin-degrading commensals in the large intestine.
Yeast Dual roles of yeast Rad51 N-terminal domain in repairing DNA double-strand breaks.
Silkworms Antheraea pernyi , Antheraea yamamai , Saturnia jonasii, , Actias aliena , Aglia japonica (Saturniidae) Limited proteolysis by a prostatic endopeptidase, the sperm-activating factor initiatorin, regulates the activation of pro-carboxypeptidase B in the seminal fluid of the silkworm, Bombyx mori.
DNA material pCW57-CMV-ssRFP-GFP-KDEL (RDB19767) , pMRX-INU-FLAG-RTN3L (RDB19781) Intrinsically Disordered Protein TEX264 Mediates ER-phagy.