• 14 Hits
  • 検索条件 : 絞込み (MeSH = Proto-Oncogene Proteins / antagonists & inhibitors*)
生物種 リソース名 タイトル
ヒト・動物細胞 MDCK(RCB0995) Down-regulation of Mcl-1 by inhibition of the PI3-K/Akt pathway is required for cell shrinkage-dependent cell death.
ヒト・動物細胞 HeLa/Fucci(RCB2812) PLK1 blockade enhances therapeutic effects of radiation by inducing cell cycle arrest at the mitotic phase.
ヒト・動物細胞 PC-9(RCB4455) ONO-7475, a Novel AXL Inhibitor, Suppresses the Adaptive Resistance to Initial EGFR-TKI Treatment in EGFR-Mutated Non-Small Cell Lung Cancer.
ヒト・動物細胞 HS-Sch-2(RCB2230) , YST-1(RCB2136) , HS-PSS(RCB2362) Drug sensitivity and resistance testing identifies PLK1 inhibitors and gemcitabine as potent drugs for malignant peripheral nerve sheath tumors.
ヒト・動物細胞 HuH-6(RCB1367) MDM4 inhibition: a novel therapeutic strategy to reactivate p53 in hepatoblastoma.
ヒト・動物細胞 HL60(RCB0041) , U-937 DE-4(RCB0435) Nitrogen-containing bisphosphonates induce apoptosis of hematopoietic tumor cells via inhibition of Ras signaling pathways and Bim-mediated activation of the intrinsic apoptotic pathway.
ヒト・動物細胞 Ba/F3 The new-generation selective ROS1/NTRK inhibitor DS-6051b overcomes crizotinib resistant ROS1-G2032R mutation in preclinical models.
ヒト・動物細胞 Y79(RCB1645) , WERI-Rb-1(RCB2146) Inhibition of polo-like kinase 1 promotes hyperthermia sensitivity via inactivation of heat shock transcription factor 1 in human retinoblastoma cells.
ヒト・動物細胞 HTOA(RCB0692) , JHOS-2(RCB1521) Methylation-associated silencing of the Wnt antagonist SFRP1 gene in human ovarian cancers.
ショウジョウバエ EDL/MAE regulates EGF-mediated induction by antagonizing Ets transcription factor Pointed.
遺伝子材料 pCMV-MAZ (RDB03219) , pGEX-hMAZ (RDB05701) MAZ-binding G4-decoy with locked nucleic acid and twisted intercalating nucleic acid modifications suppresses KRAS in pancreatic cancer cells and delays tumor growth in mice.
ヒト・動物細胞 HS-Os-1(RCB2229) , NOS-1(RCB1032) , HuO-3N1(RCB2104) Functional genome screen for therapeutic targets of osteosarcoma.
ヒト・動物細胞 MC3T3-E1(RCB1126) Statins inhibit osteoblast migration by inhibiting Rac-Akt signaling.
ヒト・動物細胞 MKN45(RCB1001) Inhibition of the PI3K-Akt signaling pathway enhances the sensitivity of Fas-mediated apoptosis in human gastric carcinoma cell line, MKN-45.