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  • 検索条件 : 絞込み (MeSH = Proto-Oncogene Proteins c-met / metabolism)
生物種 リソース名 タイトル
ヒト・動物細胞 KP4(RCB1005) LY2801653 is an orally bioavailable multi-kinase inhibitor with potent activity against MET, MST1R, and other oncoproteins, and displays anti-tumor activities in mouse xenograft models.
ヒト・動物細胞 Hep G2(RCB1648) Hepatocyte Growth Factor Enhances Antineoplastic Effect of 5-Fluorouracil by Increasing UPP1 Expression in HepG2 Cells.
ヒト・動物細胞 U251(RCB0461) , KG-1-C(RCB0270) Reduced expression of hepatocyte growth factor activator inhibitor type-2/placental bikunin (HAI-2/PB) in human glioblastomas: implication for anti-invasive role of HAI-2/PB in glioblastoma cells.
ヒト・動物細胞 MKN45(RCB1001) Combined drug action of 2-phenylimidazo[2,1-b]benzothiazole derivatives on cancer cells according to their oncogenic molecular signatures.
ヒト・動物細胞 A549(RCB0098) , LC-2/ad(RCB0440) Inhibition of ABCB1 Overcomes Cancer Stem Cell-like Properties and Acquired Resistance to MET Inhibitors in Non-Small Cell Lung Cancer.
ヒト・動物細胞 PANC-1(RCB2095) MK2461, a Multitargeted Kinase Inhibitor, Suppresses the Progression of Pancreatic Cancer by Disrupting the Interaction Between Pancreatic Cancer Cells and Stellate Cells.
ヒト・動物細胞 ST2(RCB0224) , MC3T3-E1(RCB1126) The HGF/Met/NF-κB Pathway Regulates RANKL Expression in Osteoblasts and Bone Marrow Stromal Cells.
ヒト・動物細胞 Li-7(RCB1941) TBX3 functions as a tumor suppressor downstream of activated CTNNB1 mutants during hepatocarcinogenesis.
ヒト・動物細胞 B16 melanoma(RCB1283) Glycometabolic Regulation of the Biogenesis of Small Extracellular Vesicles.
ヒト・動物細胞 MKN45(RCB1001) In Vitro and In Vivo Activity of AMG 337, a Potent and Selective MET Kinase Inhibitor, in MET-Dependent Cancer Models.
ヒト・動物細胞 RGM1(RCB0876) Epidermal growth factor receptor mediates stress-induced expression of its ligands in rat gastric epithelial cells.
ヒト・動物細胞 HS-SY-II(RCB2231) Therapeutic potential of TAS-115 via c-MET and PDGFRα signal inhibition for synovial sarcoma.
ヒト・動物細胞 GCIY(RCB0555) , ECC12(RCB1009) , KE-97(RCB1435) Saracatinib impairs the peritoneal dissemination of diffuse-type gastric carcinoma cells resistant to Met and fibroblast growth factor receptor inhibitors.
ヒト・動物細胞 MRC-5 Ability of the Met kinase inhibitor crizotinib and new generation EGFR inhibitors to overcome resistance to EGFR inhibitors.
ヒト・動物細胞 KP4(RCB1005) Monovalent antibody design and mechanism of action of onartuzumab, a MET antagonist with anti-tumor activity as a therapeutic agent.
ヒト・動物細胞 Indazoles as potential c-Met inhibitors: design, synthesis and molecular docking studies.
ヒト・動物細胞 MKN1(RCB1003) , LMSU(RCB1062) Association of amphiregulin with the cetuximab sensitivity of gastric cancer cell lines.
ヒト・動物細胞 MRC-5 Paracrine receptor activation by microenvironment triggers bypass survival signals and ALK inhibitor resistance in EML4-ALK lung cancer cells.
ヒト・動物細胞 MRC-5 Hepatocyte growth factor induces resistance to anti-epidermal growth factor receptor antibody in lung cancer.
ヒト・動物細胞 A preclinical algorithm of soluble surrogate biomarkers that correlate with therapeutic inhibition of the MET oncogene in gastric tumors.