生物種
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リソース名
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RRC ID
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タイトル
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ジャーナル
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公開日
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外部リンク
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ヒト・動物細胞
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KP4(RCB1005)
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77543
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LY2801653 is an orally bioavailable multi-kinase inhibitor with potent activity against MET, MST1R, and other oncoproteins, and displays anti-tumor activities in mouse xenograft models.
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Invest New Drugs |
2013-8-1 |
Pubmed
Full text
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ヒト・動物細胞
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Hep G2(RCB1648)
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74568
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Hepatocyte Growth Factor Enhances Antineoplastic Effect of 5-Fluorouracil by Increasing UPP1 Expression in HepG2 Cells.
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Int J Mol Sci |
2022-8-14 |
Pubmed
Full text
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ヒト・動物細胞
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U251(RCB0461)
,
KG-1-C(RCB0270)
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72296
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Reduced expression of hepatocyte growth factor activator inhibitor type-2/placental bikunin (HAI-2/PB) in human glioblastomas: implication for anti-invasive role of HAI-2/PB in glioblastoma cells.
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Int J Cancer |
2001-8-1 |
Pubmed
Full text
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ヒト・動物細胞
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MKN45(RCB1001)
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68690
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Combined drug action of 2-phenylimidazo[2,1-b]benzothiazole derivatives on cancer cells according to their oncogenic molecular signatures.
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PLoS One |
2012-1-1 |
Pubmed
Full text
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ヒト・動物細胞
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A549(RCB0098)
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LC-2/ad(RCB0440)
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67405
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Inhibition of ABCB1 Overcomes Cancer Stem Cell-like Properties and Acquired Resistance to MET Inhibitors in Non-Small Cell Lung Cancer.
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Mol Cancer Ther |
2015-11-1 |
Pubmed
Full text
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ヒト・動物細胞
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PANC-1(RCB2095)
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67201
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MK2461, a Multitargeted Kinase Inhibitor, Suppresses the Progression of Pancreatic Cancer by Disrupting the Interaction Between Pancreatic Cancer Cells and Stellate Cells.
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Pancreas |
2017-4-1 |
Pubmed
Full text
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ヒト・動物細胞
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ST2(RCB0224)
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MC3T3-E1(RCB1126)
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65021
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The HGF/Met/NF-κB Pathway Regulates RANKL Expression in Osteoblasts and Bone Marrow Stromal Cells.
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Int J Mol Sci |
2020-10-24 |
Pubmed
Full text
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ヒト・動物細胞
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Li-7(RCB1941)
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64302
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TBX3 functions as a tumor suppressor downstream of activated CTNNB1 mutants during hepatocarcinogenesis.
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J Hepatol |
2021-7-1 |
Pubmed
Full text
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ヒト・動物細胞
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B16 melanoma(RCB1283)
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63119
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Glycometabolic Regulation of the Biogenesis of Small Extracellular Vesicles.
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Cell Rep |
2020-10-13 |
Pubmed
Full text
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ヒト・動物細胞
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MKN45(RCB1001)
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61696
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In Vitro and In Vivo Activity of AMG 337, a Potent and Selective MET Kinase Inhibitor, in MET-Dependent Cancer Models.
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Mol Cancer Ther |
2016-7-1 |
Pubmed
Full text
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ヒト・動物細胞
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RGM1(RCB0876)
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61552
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Epidermal growth factor receptor mediates stress-induced expression of its ligands in rat gastric epithelial cells.
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Gastroenterology |
2001-1-1 |
Pubmed
Full text
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ヒト・動物細胞
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HS-SY-II(RCB2231)
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52223
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Therapeutic potential of TAS-115 via c-MET and PDGFRα signal inhibition for synovial sarcoma.
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BMC Cancer |
2017-5-16 |
Pubmed
Full text
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ヒト・動物細胞
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GCIY(RCB0555)
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ECC12(RCB1009)
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KE-97(RCB1435)
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44956
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Saracatinib impairs the peritoneal dissemination of diffuse-type gastric carcinoma cells resistant to Met and fibroblast growth factor receptor inhibitors.
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Cancer Sci |
2014-5-1 |
Pubmed
Full text
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ヒト・動物細胞
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MRC-5
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44834
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Ability of the Met kinase inhibitor crizotinib and new generation EGFR inhibitors to overcome resistance to EGFR inhibitors.
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PLoS One |
2013-1-1 |
Pubmed
Full text
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ヒト・動物細胞
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KP4(RCB1005)
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44547
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Monovalent antibody design and mechanism of action of onartuzumab, a MET antagonist with anti-tumor activity as a therapeutic agent.
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Proc Natl Acad Sci U S A |
2013-8-6 |
Pubmed
Full text
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ヒト・動物細胞
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44453
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Indazoles as potential c-Met inhibitors: design, synthesis and molecular docking studies.
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Eur J Med Chem |
2013-7-1 |
Pubmed
Full text
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ヒト・動物細胞
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MKN1(RCB1003)
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LMSU(RCB1062)
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43857
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Association of amphiregulin with the cetuximab sensitivity of gastric cancer cell lines.
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Int J Oncol |
2012-8-1 |
Pubmed
Full text
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ヒト・動物細胞
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MRC-5
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43816
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Paracrine receptor activation by microenvironment triggers bypass survival signals and ALK inhibitor resistance in EML4-ALK lung cancer cells.
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Clin Cancer Res |
2012-7-1 |
Pubmed
Full text
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ヒト・動物細胞
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MRC-5
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43596
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Hepatocyte growth factor induces resistance to anti-epidermal growth factor receptor antibody in lung cancer.
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J Thorac Oncol |
2012-2-1 |
Pubmed
Full text
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ヒト・動物細胞
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|
43556
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A preclinical algorithm of soluble surrogate biomarkers that correlate with therapeutic inhibition of the MET oncogene in gastric tumors.
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Int J Cancer |
2012-3-15 |
Pubmed
Full text
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