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生物種
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リソース名
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RRC ID
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タイトル
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ジャーナル
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公開日
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外部リンク
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ヒト・動物細胞
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KP4(RCB1005)
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86113
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Targeting the SHOC2-RAS interaction in RAS-mutant cancers.
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Nature |
2025-6-1 |
Pubmed
Full text
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遺伝子材料
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CSII-CMV-MCS (RDB04377)
,
pCAG-HIVgp (RDB04394)
,
pCMV-VSV-G-RSV-Rev (RDB04393)
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85095
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MICAL2 Promotes Pancreatic Cancer Growth and Metastasis.
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Cancer Res |
2025-3-14 |
Pubmed
Full text
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ヒト・動物細胞
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CACO-2(RCB0988)
,
COLO205(RCB2127)
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78173
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p53-armed oncolytic adenovirus induces autophagy and apoptosis in KRAS and BRAF-mutant colorectal cancer cells.
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PLoS One |
2023-1-1 |
Pubmed
Full text
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ヒト・動物細胞
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CACO-2(RCB0988)
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76986
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Cetuximab Enhances the Efficacy of MRTX1133, a Novel KRASG12D Inhibitor, in Colorectal Cancer Treatment.
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Anticancer Res |
2023-10-1 |
Pubmed
Full text
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ヒト・動物細胞
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Lu99(RCB1900)
,
LU65(RCB1967)
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73013
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PAK and PI3K pathway activation confers resistance to KRASG12C inhibitor sotorasib.
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Br J Cancer |
2023-1-1 |
Pubmed
Full text
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遺伝子材料
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pCMV-VSV-G-RSV-Rev (RDB04393)
,
pCAG-HIVgp (RDB04394)
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71804
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Concurrent Activation of Kras and Canonical Wnt Signaling Induces Premalignant Lesions That Progress to Extrahepatic Biliary Cancer in Mice.
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Cancer Res |
2022-5-3 |
Pubmed
Full text
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ヒト・動物細胞
,
遺伝子材料
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PANC-1(RCB2095)
,
CSII-CMV-MCS-IRES2-Bsd (RDB04385)
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69647
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Localization of KRAS downstream target ARL4C to invasive pseudopods accelerates pancreatic cancer cell invasion.
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Elife |
2021-9-30 |
Pubmed
Full text
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ヒト・動物細胞
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PC-9(RCB4455)
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68842
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Trametinib overcomes KRAS-G12V-induced osimertinib resistance in a leptomeningeal carcinomatosis model of EGFR-mutant lung cancer.
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Cancer Sci |
2021-9-1 |
Pubmed
Full text
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遺伝子材料
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pCMV-VSV-G-RSV-Rev (RDB04393)
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67731
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Oncogenic mutation or overexpression of oncogenic KRAS or BRAF is not sufficient to confer oncogene addiction.
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PLoS One |
2021-1-1 |
Pubmed
Full text
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ヒト・動物細胞
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NIH3T3
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64636
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Metabolic Adaptation to Nutritional Stress in Human Colorectal Cancer.
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Sci Rep |
2016-12-7 |
Pubmed
Full text
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ヒト・動物細胞
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DT40(RCB1464)
,
SHP2^(-) DT40(RCB1502)
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61877
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NVP-LAQ824 is a potent novel histone deacetylase inhibitor with significant activity against multiple myeloma.
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Blood |
2003-10-1 |
Pubmed
Full text
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ヒト・動物細胞
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HL60(RCB0041)
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U-937 DE-4(RCB0435)
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61871
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Nitrogen-containing bisphosphonates induce apoptosis of hematopoietic tumor cells via inhibition of Ras signaling pathways and Bim-mediated activation of the intrinsic apoptotic pathway.
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Biochem Pharmacol |
2013-1-15 |
Pubmed
Full text
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ヒト・動物細胞
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T3M-4(RCB1021)
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56893
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Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer.
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Nature |
2017-6-22 |
Pubmed
Full text
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実験動物マウス
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RBRC01828
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49646
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Mice with an Oncogenic HRAS Mutation are Resistant to High-Fat Diet-Induced Obesity and Exhibit Impaired Hepatic Energy Homeostasis.
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EBioMedicine |
2018-1-1 |
Pubmed
Full text
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ヒト・動物細胞
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F-36P(RCB0775)
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39820
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Increased D-type cyclin expression together with decreased cdc2 activity confers megakaryocytic differentiation of a human thrombopoietin-dependent hematopoietic cell line.
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J Biol Chem |
2000-2-25 |
Pubmed
Full text
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ショウジョウバエ
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11150
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Loss of cell polarity drives tumor growth and invasion through JNK activation in Drosophila.
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Curr Biol |
2006-6-6 |
Pubmed
Full text
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遺伝子材料
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AxCANCre (RDB01748)
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4779
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Requirement for C3G-dependent Rap1 activation for cell adhesion and embryogenesis.
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EMBO J |
2001-7-2 |
Pubmed
Full text
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