• 14 Hits
  • 検索条件 : 絞込み (MeSH = Proto-Oncogene Proteins p21(ras) / metabolism)
生物種 リソース名 タイトル
ヒト・動物細胞 CACO-2(RCB0988) , COLO205(RCB2127) p53-armed oncolytic adenovirus induces autophagy and apoptosis in KRAS and BRAF-mutant colorectal cancer cells.
ヒト・動物細胞 CACO-2(RCB0988) Cetuximab Enhances the Efficacy of MRTX1133, a Novel KRASG12D Inhibitor, in Colorectal Cancer Treatment.
遺伝子材料 pCMV-VSV-G-RSV-Rev (RDB04393) , pCAG-HIVgp (RDB04394) Concurrent Activation of Kras and Canonical Wnt Signaling Induces Premalignant Lesions That Progress to Extrahepatic Biliary Cancer in Mice.
ヒト・動物細胞 , 遺伝子材料 PANC-1(RCB2095) , CSII-CMV-MCS-IRES2-Bsd (RDB04385) Localization of KRAS downstream target ARL4C to invasive pseudopods accelerates pancreatic cancer cell invasion.
ヒト・動物細胞 PC-9(RCB4455) Trametinib overcomes KRAS-G12V-induced osimertinib resistance in a leptomeningeal carcinomatosis model of EGFR-mutant lung cancer.
遺伝子材料 pCMV-VSV-G-RSV-Rev (RDB04393) Oncogenic mutation or overexpression of oncogenic KRAS or BRAF is not sufficient to confer oncogene addiction.
ヒト・動物細胞 NIH3T3 Metabolic Adaptation to Nutritional Stress in Human Colorectal Cancer.
ヒト・動物細胞 DT40(RCB1464) , SHP2^(-) DT40(RCB1502) NVP-LAQ824 is a potent novel histone deacetylase inhibitor with significant activity against multiple myeloma.
ヒト・動物細胞 HL60(RCB0041) , U-937 DE-4(RCB0435) Nitrogen-containing bisphosphonates induce apoptosis of hematopoietic tumor cells via inhibition of Ras signaling pathways and Bim-mediated activation of the intrinsic apoptotic pathway.
ヒト・動物細胞 T3M-4(RCB1021) Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer.
実験動物マウス RBRC01828 Mice with an Oncogenic HRAS Mutation are Resistant to High-Fat Diet-Induced Obesity and Exhibit Impaired Hepatic Energy Homeostasis.
ヒト・動物細胞 Increased D-type cyclin expression together with decreased cdc2 activity confers megakaryocytic differentiation of a human thrombopoietin-dependent hematopoietic cell line.
ショウジョウバエ Loss of cell polarity drives tumor growth and invasion through JNK activation in Drosophila.
遺伝子材料 AxCANCre (RDB01748) Requirement for C3G-dependent Rap1 activation for cell adhesion and embryogenesis.