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  • Search Condition : Filter (MeSH = Proto-Oncogene Proteins p21(ras) / metabolism)
Species Resource Title
Human and Animal Cells CACO-2(RCB0988) , COLO205(RCB2127) p53-armed oncolytic adenovirus induces autophagy and apoptosis in KRAS and BRAF-mutant colorectal cancer cells.
Human and Animal Cells CACO-2(RCB0988) Cetuximab Enhances the Efficacy of MRTX1133, a Novel KRASG12D Inhibitor, in Colorectal Cancer Treatment.
DNA material pCMV-VSV-G-RSV-Rev (RDB04393) , pCAG-HIVgp (RDB04394) Concurrent Activation of Kras and Canonical Wnt Signaling Induces Premalignant Lesions That Progress to Extrahepatic Biliary Cancer in Mice.
Human and Animal Cells , DNA material PANC-1(RCB2095) , CSII-CMV-MCS-IRES2-Bsd (RDB04385) Localization of KRAS downstream target ARL4C to invasive pseudopods accelerates pancreatic cancer cell invasion.
Human and Animal Cells PC-9(RCB4455) Trametinib overcomes KRAS-G12V-induced osimertinib resistance in a leptomeningeal carcinomatosis model of EGFR-mutant lung cancer.
DNA material pCMV-VSV-G-RSV-Rev (RDB04393) Oncogenic mutation or overexpression of oncogenic KRAS or BRAF is not sufficient to confer oncogene addiction.
Human and Animal Cells NIH3T3 Metabolic Adaptation to Nutritional Stress in Human Colorectal Cancer.
Human and Animal Cells DT40(RCB1464) , SHP2^(-) DT40(RCB1502) NVP-LAQ824 is a potent novel histone deacetylase inhibitor with significant activity against multiple myeloma.
Human and Animal Cells HL60(RCB0041) , U-937 DE-4(RCB0435) Nitrogen-containing bisphosphonates induce apoptosis of hematopoietic tumor cells via inhibition of Ras signaling pathways and Bim-mediated activation of the intrinsic apoptotic pathway.
Human and Animal Cells T3M-4(RCB1021) Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer.
Mice RBRC01828 Mice with an Oncogenic HRAS Mutation are Resistant to High-Fat Diet-Induced Obesity and Exhibit Impaired Hepatic Energy Homeostasis.
Human and Animal Cells Increased D-type cyclin expression together with decreased cdc2 activity confers megakaryocytic differentiation of a human thrombopoietin-dependent hematopoietic cell line.
Drosophila Loss of cell polarity drives tumor growth and invasion through JNK activation in Drosophila.
DNA material AxCANCre (RDB01748) Requirement for C3G-dependent Rap1 activation for cell adhesion and embryogenesis.