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  • Search Condition : Filter (MeSH = Pyrimidines / chemistry)
Species Resource Title
Human and Animal Cells 293T(RCB2202) Anti-tumor efficacy of a novel CLK inhibitor via targeting RNA splicing and MYC-dependent vulnerability.
Human and Animal Cells Li-7(RCB1941) ASP5878, a Novel Inhibitor of FGFR1, 2, 3, and 4, Inhibits the Growth of FGF19-Expressing Hepatocellular Carcinoma.
Human and Animal Cells PC-9(RCB4455) Discovery of 1-{(3R,4R)-3-[({5-Chloro-2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)methyl]-4-methoxypyrrolidin-1-yl}prop-2-en-1-one (PF-06459988), a Potent, WT Sparing, Irreversible Inhibitor of T790M-Containing EGFR Mutants.
DNA material , Human and Animal Cells Genome Network Project Human cDNA Clone IRAK029O09 (HGX011945) , A549(RCB0098) Discovery of anti-cell migration activity of an anti-HIV heterocyclic compound by identification of its binding protein hnRNP M.
Prokaryotes E. coli Competence of Thiamin Diphosphate-Dependent Enzymes with 2'-Methoxythiamin Diphosphate Derived from Bacimethrin, a Naturally Occurring Thiamin Anti-vitamin.
Human and Animal Cells 293T(RCB2202) Inhibition of veratridine-induced delayed inactivation of the voltage-sensitive sodium channel by synthetic analogs of crambescin B.
DNA material pENTER-EGFR wild-type (RDB15488) , pENTER-EGFR Del19 (RDB15489) , pENTER-EGFR T790M/del19 (RDB15490) , pENTER-EGFR C797S/del19 (RDB15491) , pENTER-EGFR C797S/T790M/del19 (RDB15492) , pENTER-EGFR L858R (RDB15493) , pENTER-EGFR T790M/L858R (RDB15494) , pENTER-EGFR C797S/L858R (RDB15495) , pENTER-EGFR C797S/T790M/L858R (RDB15496). Brigatinib combined with anti-EGFR antibody overcomes osimertinib resistance in EGFR-mutated non-small-cell lung cancer.