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  • Search Condition : Filter (MeSH = Transcriptional Coactivator with PDZ-Binding Motif Proteins)
Species Resource Title
Human and Animal Cells G-415(RCB2640) Co-expression of YAP and TAZ associates with chromosomal instability in human cholangiocarcinoma.
Human and Animal Cells Li-7(RCB1941) Statin attenuates cell proliferative ability via TAZ (WWTR1) in hepatocellular carcinoma.
Human and Animal Cells Lu-134-A(RCB0466) , Lu-134-B(RCB0467) , Lu-139(RCB0469) YAP and TAZ modulate cell phenotype in a subset of small cell lung cancer.
Medaka databases yap1b, a divergent Yap/Taz family member, cooperates with yap1 in survival and morphogenesis via common transcriptional targets.
Human and Animal Cells HuCCT1(RCB1960) Type I collagen deposition via osteoinduction ameliorates YAP/TAZ activity in 3D floating culture clumps of mesenchymal stem cell/extracellular matrix complexes.
DNA material pKM2L-phIL1B (RDB05526) TAZ activation by Hippo pathway dysregulation induces cytokine gene expression and promotes mesothelial cell transformation.
DNA material , Human and Animal Cells pAxCAwt (RDB01678) , ST2(RCB0224) Interaction of LEF1 with TAZ is necessary for the osteoblastogenic activity of Wnt3a.
Human and Animal Cells ST2(RCB0224) Vinculin promotes nuclear localization of TAZ to inhibit ECM stiffness-dependent differentiation into adipocytes.
Human and Animal Cells Hep G2(RCB1648) , HuH-7(RCB1942) miR-9-3p plays a tumour-suppressor role by targeting TAZ (WWTR1) in hepatocellular carcinoma cells.
DNA material pLL3.7 K122 FH-TAZ-ires-GFP-TEAD-responsive-H2B mCherry (RDB13967) , pFLAG-human yes-associated protein (YAP)1 (RDB13968) , pClneoMyc-LATS1 (RDB13969) , pClneoMyc-LATS2 (RDB13970) , pClneoLuc-PP1A (RDB13971) , pClneoLuc-PP2A (RDB13972). A cell-based screening for TAZ activators identifies ethacridine, a widely used antiseptic and abortifacient, as a compound that promotes dephosphorylation of TAZ and inhibits adipogenesis in C3H10T1/2 cells.