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  • 8 Hits
  • Search Condition : Filter (MeSH = Trinucleotide Repeat Expansion)
Species Resource Title
Human and Animal Cells PC-12(RCB0009) Toxicity of internalized polyalanine to cells depends on aggregation.
DNA material pCAG-HIVgp (RDB04394) , pCMV-VSV-G-RSV-Rev (RDB04393) Unveiling synapse pathology in spinal bulbar muscular atrophy by genome-wide transcriptome analysis of purified motor neurons derived from disease specific iPSCs.
DNA material pCAG-HIVgp (RDB04394) , pCMV-VSV-G (RDB04392) , CSII-CMV-MCS-IRES2-Venus (RDB04383). Transgenic Monkey Model of the Polyglutamine Diseases Recapitulating Progressive Neurological Symptoms.
C.elegans tm1489 Expression of an expanded CGG-repeat RNA in a single pair of primary sensory neurons impairs olfactory adaptation in Caenorhabditis elegans.
Drosophila 7459R-2 Huntington disease arises from a combinatory toxicity of polyglutamine and copper binding.
Drosophila Muscleblind, BSF and TBPH are mislocalized in the muscle sarcomere of a Drosophila myotonic dystrophy model.
Drosophila 13387R-1 , 13387R-4 Expanded polyglutamine domain possesses nuclear export activity which modulates subcellular localization and toxicity of polyQ disease protein via exportin-1.
Mice , Human and Animal Cells RBRC00344 , RBRC00373 , COS-7(RCB0539) , SK-N-SH(RCB0426) Hsp105alpha suppresses the aggregation of truncated androgen receptor with expanded CAG repeats and cell toxicity.