• 21 Hits
  • 検索条件 : 絞込み (MeSH = Tumor Suppressor Protein p53* / genetics)
生物種 リソース名 タイトル
ヒト・動物細胞 KMST-6(RCB1955) In vitro screening of compounds for targeting gastric cancer with Y220C p53 mutation: a molecule combining zinc chelation and a Michael acceptor drives CDKN1 and BBC3 expression to restore a p53-dependent cytotoxicity.
ヒト・動物細胞 LA-N-5(RCB0485) P53-armed Oncolytic Adenovirus Enhances the Efficacy of PD-1 Blockade in Neuroblastoma by Inducing Immunogenic Cell Death.
ヒト・動物細胞 TIG-3(RCB4468) Inhibition of PSF Activity Overcomes Resistance to Treatment in Cancers Harboring Mutant p53.
ヒト・動物細胞 TE-6(RCB1950) Zinc Finger Protein 82 regulates p53 protein stability through histone deacetylase and enhances neo-adjuvant chemotherapy in esophageal cancer.
遺伝子材料 pPCIH-vector (RDB20967) , pPCIP-flag-SLFN11 (E209A/E214A) (RDB20964) , pPCIH-flag-SLFN11 (WT) (RDB20968) , pPCIH-flag-SLFN11 (E669Q) (RDB20969) , pPCIH-flag-SLFN11 (E209A/E214A) (RDB20970) , pPCIH-flag-SLFN11 (K652E) (RDB20971) , pPCIH-flag-SLFN11 (S753D) (RDB20972) SLFN11-mediated ribosome biogenesis impairment induces TP53-independent apoptosis.
ヒト・動物細胞 HuCCT1(RCB1960) A base editing platform for the correction of cancer driver mutations unmasks conserved p53 transcription programs.
ヒト・動物細胞 HPS2478(HPS2478) , HPS2508(HPS2508) , HPS3131(HPS3131) , HPS3676(HPS3676) , HPS3681(HPS3681) , HPS3686(HPS3686) , HPS3692(HPS3692) , HPS3696(HPS3696) , HPS3810(HPS3810) , HPS4115(HPS4115) Highly efficient XIST reactivation in female hPSC by transient dual inhibition of TP53 and DNA methylation during Cas9 mediated genome editing.
ヒト・動物細胞 KhES-3(HES0003) , KhES-1(HES0001) p53-inducible lncRNA LOC644656 causes genotoxic stress-induced stem cell maldifferentiation and cancer chemoresistance.
ヒト・動物細胞 T98G(RCB1954) The balance among radiation-induced cell death pathways in the p53-mutant human glioblastoma cell line T98G: A preliminary study.
ゼブラフィッシュ Tg(fli1a:h2b-mCherry)ncv31Tg Haploidy-linked cell proliferation defects limit larval growth in zebrafish.
ヒト・動物細胞 NOS-1(RCB1032) Myc upregulates Ggct, γ-glutamylcyclotransferase to promote development of p53-deficient osteosarcoma.
ヒト・動物細胞 B16 melanoma KDM4B Histone Demethylase Inhibition Attenuates Tumorigenicity of Malignant Melanoma Cells by Overriding the p53-Mediated Tumor Suppressor Pathway.
ヒト・動物細胞 HCT116(RCB2979) , COLO205(RCB2127) SHARPIN is a novel gene of colorectal cancer that promotes tumor growth potentially via inhibition of p53 expression.
ショウジョウバエ 15862R-2 , 7626R-3 Dominant suppressor genes of p53-induced apoptosis in Drosophila melanogaster.
ヒト・動物細胞 NB69(RCB0480) Polycomb group protein BMI1 protects neuroblastoma cells against DNA damage-induced apoptotic cell death.
ヒト・動物細胞 HuCCT1(RCB1960) , NIH:OVCAR-3(RCB2135) , A549(RCB0098) , Saos-2 Colletofragarone A2 Inhibits Cancer Cell Growth In Vivo and Leads to the Degradation and Aggregation of Mutant p53.
ヒト・動物細胞 RMS-YM(RCB1695) Nucleolar Stress Response via Ribosomal Protein L11 Regulates Topoisomerase Inhibitor Sensitivity of P53-Intact Cancers.
ヒト・動物細胞 TUHR4TKB(RCB1198) , TUHR10TKB(RCB1275) , TUHR14TKB(RCB1383) , RCC10RGB(RCB1151) Sensitivity of VHL mutant kidney cancers to HIF2 inhibitors does not require an intact p53 pathway.
実験動物マウス RBRC01361 p53 deficiency promotes bone regeneration by functional regulation of mesenchymal stromal cells and osteoblasts.
ヒト・動物細胞 MKN7(RCB0999) , MKN45(RCB1001) , MKN74(RCB1002) , HGC-27(RCB0500) , NUGC-4(RCB1939) LRRC8A influences the growth of gastric cancer cells via the p53 signaling pathway.