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生物種
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リソース名
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RRC ID
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タイトル
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ジャーナル
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公開日
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外部リンク
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ヒト・動物細胞
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KMST-6(RCB1955)
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88484
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In vitro screening of compounds for targeting gastric cancer with Y220C p53 mutation: a molecule combining zinc chelation and a Michael acceptor drives CDKN1 and BBC3 expression to restore a p53-dependent cytotoxicity.
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J Enzyme Inhib Med Chem |
2026-12-1 |
Pubmed
Full text
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ヒト・動物細胞
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LA-N-5(RCB0485)
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87252
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P53-armed Oncolytic Adenovirus Enhances the Efficacy of PD-1 Blockade in Neuroblastoma by Inducing Immunogenic Cell Death.
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Anticancer Res |
2026-4-1 |
Pubmed
Full text
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ヒト・動物細胞
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TIG-3(RCB4468)
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86043
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Inhibition of PSF Activity Overcomes Resistance to Treatment in Cancers Harboring Mutant p53.
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Mol Cancer Ther |
2025-3-4 |
Pubmed
Full text
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ヒト・動物細胞
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TE-6(RCB1950)
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86012
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Zinc Finger Protein 82 regulates p53 protein stability through histone deacetylase and enhances neo-adjuvant chemotherapy in esophageal cancer.
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Cell Death Dis |
2025-10-6 |
Pubmed
Full text
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遺伝子材料
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pPCIH-vector (RDB20967)
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pPCIP-flag-SLFN11 (E209A/E214A) (RDB20964)
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pPCIH-flag-SLFN11 (WT) (RDB20968)
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pPCIH-flag-SLFN11 (E669Q) (RDB20969)
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pPCIH-flag-SLFN11 (E209A/E214A) (RDB20970)
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pPCIH-flag-SLFN11 (K652E) (RDB20971)
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pPCIH-flag-SLFN11 (S753D) (RDB20972)
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85546
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SLFN11-mediated ribosome biogenesis impairment induces TP53-independent apoptosis.
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Mol Cell |
2025-3-6 |
Pubmed
Full text
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ヒト・動物細胞
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HuCCT1(RCB1960)
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85357
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A base editing platform for the correction of cancer driver mutations unmasks conserved p53 transcription programs.
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Genome Biol |
2025-7-22 |
Pubmed
Full text
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ヒト・動物細胞
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HPS2478(HPS2478)
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HPS2508(HPS2508)
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HPS3131(HPS3131)
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HPS3676(HPS3676)
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HPS3681(HPS3681)
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HPS3686(HPS3686)
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HPS3692(HPS3692)
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HPS3696(HPS3696)
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HPS3810(HPS3810)
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HPS4115(HPS4115)
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85340
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Highly efficient XIST reactivation in female hPSC by transient dual inhibition of TP53 and DNA methylation during Cas9 mediated genome editing.
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Stem Cell Res Ther |
2025-7-18 |
Pubmed
Full text
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ヒト・動物細胞
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KhES-3(HES0003)
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KhES-1(HES0001)
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84973
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p53-inducible lncRNA LOC644656 causes genotoxic stress-induced stem cell maldifferentiation and cancer chemoresistance.
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Nat Commun |
2025-5-23 |
Pubmed
Full text
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ヒト・動物細胞
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T98G(RCB1954)
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84971
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The balance among radiation-induced cell death pathways in the p53-mutant human glioblastoma cell line T98G: A preliminary study.
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Biomed Res |
2025-1-1 |
Pubmed
Full text
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ゼブラフィッシュ
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Tg(fli1a:h2b-mCherry)ncv31Tg
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83862
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Haploidy-linked cell proliferation defects limit larval growth in zebrafish.
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Open Biol |
2024-10-1 |
Pubmed
Full text
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ヒト・動物細胞
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NOS-1(RCB1032)
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82775
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Myc upregulates Ggct, γ-glutamylcyclotransferase to promote development of p53-deficient osteosarcoma.
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Cancer Sci |
2024-9-1 |
Pubmed
Full text
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ヒト・動物細胞
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B16 melanoma
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82513
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KDM4B Histone Demethylase Inhibition Attenuates Tumorigenicity of Malignant Melanoma Cells by Overriding the p53-Mediated Tumor Suppressor Pathway.
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J Cell Biochem |
2024-10-2 |
Pubmed
Full text
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ヒト・動物細胞
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HCT116(RCB2979)
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COLO205(RCB2127)
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81936
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SHARPIN is a novel gene of colorectal cancer that promotes tumor growth potentially via inhibition of p53 expression.
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Int J Oncol |
2024-12-1 |
Pubmed
Full text
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ショウジョウバエ
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15862R-2
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7626R-3
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81848
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Dominant suppressor genes of p53-induced apoptosis in Drosophila melanogaster.
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G3 (Bethesda) |
2024-9-4 |
Pubmed
Full text
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ヒト・動物細胞
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NB69(RCB0480)
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78726
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Polycomb group protein BMI1 protects neuroblastoma cells against DNA damage-induced apoptotic cell death.
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Exp Cell Res |
2023-1-1 |
Pubmed
Full text
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ヒト・動物細胞
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HuCCT1(RCB1960)
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NIH:OVCAR-3(RCB2135)
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A549(RCB0098)
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Saos-2
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77095
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Colletofragarone A2 Inhibits Cancer Cell Growth In Vivo and Leads to the Degradation and Aggregation of Mutant p53.
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Chem Res Toxicol |
2022-9-19 |
Pubmed
Full text
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ヒト・動物細胞
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RMS-YM(RCB1695)
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74163
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Nucleolar Stress Response via Ribosomal Protein L11 Regulates Topoisomerase Inhibitor Sensitivity of P53-Intact Cancers.
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Int J Mol Sci |
2022-12-15 |
Pubmed
Full text
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ヒト・動物細胞
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TUHR4TKB(RCB1198)
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TUHR10TKB(RCB1275)
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TUHR14TKB(RCB1383)
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RCC10RGB(RCB1151)
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70157
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Sensitivity of VHL mutant kidney cancers to HIF2 inhibitors does not require an intact p53 pathway.
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Proc Natl Acad Sci U S A |
2022-4-5 |
Pubmed
Full text
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実験動物マウス
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RBRC01361
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69960
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p53 deficiency promotes bone regeneration by functional regulation of mesenchymal stromal cells and osteoblasts.
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J Bone Miner Metab |
2022-5-1 |
Pubmed
Full text
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ヒト・動物細胞
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MKN7(RCB0999)
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MKN45(RCB1001)
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MKN74(RCB1002)
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HGC-27(RCB0500)
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NUGC-4(RCB1939)
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64357
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LRRC8A influences the growth of gastric cancer cells via the p53 signaling pathway.
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Gastric Cancer |
2021-9-1 |
Pubmed
Full text
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