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論文 - 一覧

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  • 検索条件 : 絞込み (MeSH = Tumor Suppressor Protein p53* / metabolism)
生物種 リソース名 タイトル
遺伝子材料 Genome Network Project (GNP) Human cDNA IRAK069P02 (HGX027962) Diamond-Blackfan anemia gene product RPS19 counteracts SET to maintain p53 transcriptional activity and tumor suppressor function.
ヒト・動物細胞 KMST-6(RCB1955) In vitro screening of compounds for targeting gastric cancer with Y220C p53 mutation: a molecule combining zinc chelation and a Michael acceptor drives CDKN1 and BBC3 expression to restore a p53-dependent cytotoxicity.
ヒト・動物細胞 LA-N-5(RCB0485) P53-armed Oncolytic Adenovirus Enhances the Efficacy of PD-1 Blockade in Neuroblastoma by Inducing Immunogenic Cell Death.
ヒト・動物細胞 MC3T3-E1(RCB1126) C4ST-1 Overexpression Suppresses Osteoblast Differentiation via a Wnt/β-Catenin-p53 Axis.
ヒト・動物細胞 TIG-3(RCB4468) Inhibition of PSF Activity Overcomes Resistance to Treatment in Cancers Harboring Mutant p53.
ヒト・動物細胞 TE-6(RCB1950) Zinc Finger Protein 82 regulates p53 protein stability through histone deacetylase and enhances neo-adjuvant chemotherapy in esophageal cancer.
遺伝子材料 pPCIH-vector (RDB20967) , pPCIP-flag-SLFN11 (E209A/E214A) (RDB20964) , pPCIH-flag-SLFN11 (WT) (RDB20968) , pPCIH-flag-SLFN11 (E669Q) (RDB20969) , pPCIH-flag-SLFN11 (E209A/E214A) (RDB20970) , pPCIH-flag-SLFN11 (K652E) (RDB20971) , pPCIH-flag-SLFN11 (S753D) (RDB20972) SLFN11-mediated ribosome biogenesis impairment induces TP53-independent apoptosis.
ヒト・動物細胞 HuCCT1(RCB1960) A base editing platform for the correction of cancer driver mutations unmasks conserved p53 transcription programs.
ヒト・動物細胞 HPS2478(HPS2478) , HPS2508(HPS2508) , HPS3131(HPS3131) , HPS3676(HPS3676) , HPS3681(HPS3681) , HPS3686(HPS3686) , HPS3692(HPS3692) , HPS3696(HPS3696) , HPS3810(HPS3810) , HPS4115(HPS4115) Highly efficient XIST reactivation in female hPSC by transient dual inhibition of TP53 and DNA methylation during Cas9 mediated genome editing.
ヒト・動物細胞 LA-N-5(RCB0485) , SK-N-SH(RCB0426) Pharmacologic inhibition of BMI1 exerts antitumor effects against MYCN-amplified neuroblastoma, with activation of the p53 pathway.
ヒト・動物細胞 KhES-3(HES0003) , KhES-1(HES0001) p53-inducible lncRNA LOC644656 causes genotoxic stress-induced stem cell maldifferentiation and cancer chemoresistance.
ヒト・動物細胞 T98G(RCB1954) The balance among radiation-induced cell death pathways in the p53-mutant human glioblastoma cell line T98G: A preliminary study.
ゼブラフィッシュ Tg(fli1a:h2b-mCherry)ncv31Tg Haploidy-linked cell proliferation defects limit larval growth in zebrafish.
ヒト・動物細胞 ACC-MESO-1(RCB2292) Cytoplasmic HuR Expression Enhances Chemoresistance in Pleural Mesothelioma Through Increased Expression of CALB2, Promotion of the E2F Pathway, and Suppression of the p53 Pathway.
ヒト・動物細胞 NOS-1(RCB1032) Myc upregulates Ggct, γ-glutamylcyclotransferase to promote development of p53-deficient osteosarcoma.
ヒト・動物細胞 B16 melanoma KDM4B Histone Demethylase Inhibition Attenuates Tumorigenicity of Malignant Melanoma Cells by Overriding the p53-Mediated Tumor Suppressor Pathway.
実験動物マウス RBRC09525 NF90-NF45 is essential for β cell compensation under obesity-inducing metabolic stress through suppression of p53 signaling pathway.
ヒト・動物細胞 HCT116(RCB2979) , COLO205(RCB2127) SHARPIN is a novel gene of colorectal cancer that promotes tumor growth potentially via inhibition of p53 expression.
ショウジョウバエ 15862R-2 , 7626R-3 Dominant suppressor genes of p53-induced apoptosis in Drosophila melanogaster.
遺伝子材料 pCAG-HIVgp (RDB04394) , pCMV-VSV-G-RSV-Rev (RDB04393) DNA damage-induced cellular senescence is regulated by 53BP1 accumulation in the nuclear foci and phase separation.