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  • Search Condition : Filter (MeSH = Tumor Suppressor Proteins / metabolism)
Species Resource Title
Human and Animal Cells SAS(RCB1974) , 293gp(RCB2354) Inhibition of PRMT5/MEP50 Arginine Methyltransferase Activity Causes Cancer Vulnerability in NDRG2low Adult T-Cell Leukemia/Lymphoma.
Drosophila DGRC#115288 The Drosophila tumour suppressor Lgl and Vap33 activate the Hippo pathway through a dual mechanism.
DNA material pCAGGS-myc-NES-shootin1a (261-377) (REB19943) Shootin1-cortactin interaction mediates signal-force transduction for axon outgrowth.
Drosophila 9293Ra-2  Tctp, a unique Ing5-binding partner, inhibits the chromatin binding of Enok in Drosophila.
DNA material pMXsIP-GFP-VPS33A (RDB19783) , pMRXIP-VPS16-GFP (RDB19787) The HOPS complex mediates autophagosome-lysosome fusion through interaction with syntaxin 17.
General Microbes JCM1395 Gut commensals suppress interleukin-2 production through microRNA-200/BCL11B and microRNA-200/ETS-1 axes in lamina propria leukocytes of murine large intestine.
Human and Animal Cells HuH-7(RCB1366) STAT5A modulates CDYL2/SLC7A6 pathway to inhibit the proliferation and invasion of hepatocellular carcinoma by targeting to mTORC1.
Human and Animal Cells B16F10(RCB2630) , CTLL-2(RCB0637) MK-6, a novel not-α IL-2, elicits a potent antitumor activity by improving the effector to regulatory T cell balance.
Human and Animal Cells THP-1(RCB1189) , 293(RCB1637) , 293T(RCB2202) DNA damage enhances integration of HIV-1 into macrophages by overcoming integrase inhibition.
Human and Animal Cells HS-Sch-2(RCB2230) , YST-1(RCB2136) , HS-PSS(RCB2362) Drug sensitivity and resistance testing identifies PLK1 inhibitors and gemcitabine as potent drugs for malignant peripheral nerve sheath tumors.
Zebrafish Tg(UAS:RFP) , Tg(UAS:GFP) Hippo signaling determines the number of venous pole cells that originate from the anterior lateral plate mesoderm in zebrafish.
Human and Animal Cells TE-15(RCB1951) , Kato III(RCB2088) Epigenetic silencing of HOPX contributes to cancer aggressiveness in breast cancer.
Human and Animal Cells A431 Ras and TGF-β signaling enhance cancer progression by promoting the ΔNp63 transcriptional program.
Drosophila DGRC#112001 , DGRC#109126 Homeostatic Regulation of ROS-Triggered Hippo-Yki Pathway via Autophagic Clearance of Ref(2)P/p62 in the Drosophila Intestine.
Human and Animal Cells ACC-MESO-1(RCB2292) , ACC-MESO-4(RCB2293) Functional Genomic Screen in Mesothelioma Reveals that Loss of Function of BRCA1-Associated Protein 1 Induces Chemoresistance to Ribonucleotide Reductase Inhibition.
Human and Animal Cells 201B7(HPS0063) , 253G1(HPS0002) Culture under low physiological oxygen conditions improves the stemness and quality of induced pluripotent stem cells.
Human and Animal Cells DU145(RCB2143) , PC-3(RCB2145) Basic helix-loop-helix transcription factor DEC2 functions as an anti-apoptotic factor during paclitaxel-induced apoptosis in human prostate cancer cells.
Drosophila 31935R-3 The Warburg Micro Syndrome-associated Rab3GAP-Rab18 module promotes autolysosome maturation through the Vps34 Complex I.
Human and Animal Cells C2C12(RCB0987) IGF-1 regulate the expression of uncoupling protein 2 via FOXO1.
Drosophila Hyperinsulinemia Drives Epithelial Tumorigenesis by Abrogating Cell Competition.