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  • Search Condition : Filter (MeSH = Ubiquitin Thiolesterase / metabolism*)
Species Resource Title
C.elegans tm2550 , tm526 , tm2267 The evolutionarily conserved deubiquitinase UBH1/UCH-L1 augments DAF7/TGF-β signaling, inhibits dauer larva formation, and enhances lung tumorigenesis.
Human and Animal Cells C2C12(RCB0987) Inhibition of ubiquitin-specific protease 2 causes accumulation of reactive oxygen species, mitochondria dysfunction, and intracellular ATP decrement in C2C12 myoblasts.
Zebrafish Tg(sox17:EGFP) EGF receptor kinase suppresses ciliogenesis through activation of USP8 deubiquitinase.
DNA material CSII-EF-MCS (RDB04378). EGF receptor kinase suppresses ciliogenesis through activation of USP8 deubiquitinase.
Drosophila The deubiquitinase UCHL5/UCH37 positively regulates Hedgehog signaling by deubiquitinating Smoothened.
DNA material Genome Network Project Human cDNA IRAK168O08 (HGY067544) Tandem UIMs confer Lys48 ubiquitin chain substrate preference to deubiquitinase USP25.
DNA material pENTR-Bsd-IRES-Usp10 WT (RDB15315) , pENTR-Bsd-IRES-Usp10 77-792 (RDB15316) , pENTR-Bsd-IRES-Usp10 95-792 (RDB15317) , pENTR-Bsd-IRES-Usp10 C418A (RDB15318) , pENTR-Bsd-IRES-GFP (RDB15319) , pENTR-mUSP10 (RDB15325) , CS-CMV-Bsd-IRES-Usp10 WT (RDB15320) , CS-CMV-Bsd-IRES-Usp10 77-792 (RDB15321) , CS-CMV-Bsd-IRES-Usp10 95-792 (RDB15322) , CS-CMV-Bsd-IRES-Usp10 C418A (RDB15323) , ... USP10 Is an Essential Deubiquitinase for Hematopoiesis and Inhibits Apoptosis of Long-Term Hematopoietic Stem Cells.
Human and Animal Cells TGBC1TKB(RCB1129) , TGBC2TKB(RCB1130) , PANC-1(RCB2095) , PK-1(RCB1972) , PK-45P(RCB2141) , PK-59(RCB1901) Cancer detection by ubiquitin carboxyl-terminal esterase L1 methylation in pancreatobiliary fluids.
DNA material pCAG-HIVgp (RDB04394) , pCMV-VSV-G-RSV-Rev (RDB04393). 53BP1 and USP28 mediate p53 activation and G1 arrest after centrosome loss or extended mitotic duration.